Insulin shock therapy is a treatment for schizophrenia, psychosis and drug addiction which involves injecting a patient with massive amounts of insulin, which causes convulsions and coma. It was discovered by Polish researcher Manfred Sakel in 1933 and was used well until the 1950s. Jump to: navigation, search This article is about the mental state. ... Drug addiction, or dependency is the compulsive use of drugs, to the point where the user has no effective choice but to continue use. ... Jump to: navigation, search The structure of insulin Red: carbon; green: oxygen; blue: nitrogen; pink: sulfur. ... This article is about the medical condition. ... This article is in need of attention from an expert on the subject. ... Manfred Joshua Sakel, Polish neurophysiologist and psychiatrist, was born on June 6, 1900, in Nadvorna, in the former Austria-Hungary Empire (now Ukraine). ... Jump to: navigation, search 1933 was a common year starting on Sunday (link will take you to calendar). ... Jump to: navigation, search // Events and trends The 1950s in Western society was marked with a sharp rise in the economy for the first time in almost 30 years and return to the 1920s-type consumer society built on credit and boom-times, as well as the height of the...
Insulin is a polypeptide hormone, which participates in the regulation of carbohydrate, fat and protein metabolism.
The hypoglycemic action of Insulin decreases when it is applied simultaneously with glucagon, adrenomimetics, betablockers, phenothiazine derivatives, salicylates, butadion, glycocorticoids, preparations from the posterior part of hypophysis, gas narcotics, thiazide diuretics and urosemid, while iprasid, clofibrate, ethyl alcohol and oral antidiabetic drugs increase it.
Insulin and strophantine have a contrary action on the metabolism and contractility of the myocardium, hence a mutual reduction and even inversion of their effects are possible.
Insulinshocktherapy (IST, also called InsulinComaTherapy) was used as a treatment for schizophrenia, psychosis and drug addiction, involving injecting the patient with massive amounts of insulin, which causes convulsions and coma.
InsulinShockTherapy is often viewed as a cruel practice with no reliable evidence of evidence beyond a simple shock or placebo effect.
IST had a higher apparent success rate in schizophrenics who were ill for less than two years, as this was also the time period when ‘spontaneous recovery’ was most common.