InterPro is a database of protein families, domains and functional sites in which identifiable features found in known proteins can be applied to unknown protein sequences.

The database is available for text- and sequence-based searches via a webserver (http://www.ebi.ac.uk/interpro), and for download by anonymous FTP (ftp://ftp.ebi.ac.uk/pub/databases/interpro).

To cite a particular InterPro article in Wikipedia, use the template of the form {{InterPro|IPRxxxxxx}}, where IPRxxxxxx is an InterPro accession number, for instance InterPro IPR000001. An accession number in bioinformatics is a unique identifier given to a DNA or protein sequence record to allow for tracking of different versions of that sequence record and the associated sequence over time in a single data repository. ...

See also

• Pfam
• Protein family
• Sequence motif

The Pfam database stores protein sequence alignments and represents these by Hidden Markov Models. ... A protein family is a group of evolutionarily related proteins. ... In genetics, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and has, or is conjectured to have, a biological significance. ...

References

• Mulder, N.J., Apweiler, R., Attwood, T.K., Bairoch, A., Bateman, A., Binns, D., Bradley, P., Bork, P., Bucher, P., Cerutti, L., Copley, R., Courcelle, E., Das, U., Durbin, R., Fleischmann, W., Gough, J., Haft, D., Harte, N., Hulo, N., Kahn, D., Kanapin, A., Krestyaninova, M., Lonsdale, D., Lopez, R., Letunic, I., Madera, M., Maslen, J., McDowall, J., Mitchell, A., Nikolskaya, A.N., Orchard, S., Pagni, M., Ponting, C.P., Quevillon, E., Selengut, J., Sigrist, C.J., Silventoinen, V., Studholme, D.J., Vaughan, R. and Wu, C.H. (2005). "InterPro, progress and status in 2005". Nucleic Acids Res. 33: D201–D205. PMID 15608177. 
• Quevillon, E., Silventoinen, V., Pillai, S., Harte, N., Mulder, N., Apweiler, R. and Lopez, R. (2005). "InterProScan: protein domains identifier". Nucleic Acids Res. 33: W116–W120. PMID 15980438. 

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