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The intermembrane space is the region between the inner membrane and the outer membrane of a mitochondrion or a chloroplast. The main function of the intermembrane space is nucleotide phosphorylation. The inner membrane is a membrane (phospholipid bilayer) of an organelle that is within the outer membrane. ...
Cross-section of a mitochondrion, showing: (1) inner membrane, (2) outer membrane, (3) cristae, (4) matrix The outer membrane refers to the outside membrane of an organelle which surrounds the rest of the organelle components. ...
In cell biology, a mitochondrion (plural mitochondria) (from Greek mitos thread + khondrion granule) is an organelle, variants of which are found in most eukaryotic cells[1][1]. Mitochondria are sometimes described as cellular power plants, because their primary function is to convert organic materials into energy in the form of...
The inside of a chloroplast Chloroplasts are organelles found in plant cells and eukaryotic algae that conduct photosynthesis. ...
A nucleotide is a chemical compound that consists of a heterocyclic base, a sugar, and one or more phosphate groups. ...
Phosphorylation is the addition of a phosphate (PO4) group to a protein or a small molecule. ...
Channel proteins called porins in the outer membrane allow free movement of ions and small molecules into the intermembrane space. This means that it is essentially continuous with the cytosol in terms of the solutes relevant for the functioning of these organelles. Enzymes destined for the mitochondrial matrix or the stroma can pass through the intermembrane space via transport through translocators. These are known as translocase of the outer mitochondria membrane (TOM) and translocase of the inner mitochondrial membrane (TIM) in mitochondria and translocase of the outer chloroplast membrane (TOC) and translocase of the inner chloroplast membrane (TIC) in chloroplasts. It tends to have a low pH because of the proton gradient which results when protons are pumped from the mitochondrial matrix into the intermembrane space during electron transport. The structures responsible for this are coenzyme Q, NADH coenzyme Q oxidoreductase complex (complex I), succinate-coenzyme Q oxidoreductase complex (complex II), and coenzyme Q-cytochrome c oxidoreductase complex (complex III). A representation of the 3D structure of myoglobin, showing coloured alpha helices. ...
Porins are transmembrane proteins that are large enough to facilitate passive diffusion. ...
Cross-section of a mitochondrion, showing: (1) inner membrane, (2) outer membrane, (3) cristae, (4) matrix The outer membrane refers to the outside membrane of an organelle which surrounds the rest of the organelle components. ...
// An ion is an atom or a group of atoms (a chemical substance), or subatomic particle, with a net electric charge. ...
In chemistry, a molecule is an aggregate of at least two atoms in a definite arrangement held together by special forces. ...
ÃThe cytosol (as opposed fatty cytoplasm, which also includes the organelles) is the internal fluid of the cell, and a large part of cell metabolism occurs here. ...
A substance is soluble in a fluid if it dissolves in the fluid. ...
Schematic of typical animal cell, showing subcellular components. ...
Ribbon diagram of the enzyme TIM. TIM is catalytically perfect, meaning its conversion rate is limited, or nearly limited to its substrate diffusion rate. ...
In biology, the word matrix is used for the material between animal or plant cells, or generally the material (or tissue) in which more specialized structures are embedded, and also specifically for one part of the mitochondrion. ...
Stroma can refer to: The connective supportive framework of a biological cell, tissue, or organ. ...
Tom can be an abbreviated version of the given name Thomas. ...
Tim is an album released in October 1985 on Sire Records by the alternative rock band The Replacements. ...
In cell biology, a mitochondrion (plural mitochondria) (from Greek mitos thread + khondrion granule) is an organelle, variants of which are found in most eukaryotic cells[1][1]. Mitochondria are sometimes described as cellular power plants, because their primary function is to convert organic materials into energy in the form of...
The inside of a chloroplast Chloroplasts are organelles found in plant cells and eukaryotic algae that conduct photosynthesis. ...
The title of this article should be pH. The initial letter is capitalized due to technical restrictions. ...
An ion gradient is a concentration gradient of ions, it can be called an electrochemical potential gradient of ions across membranes. ...
Properties In physics, the proton (Greek proton = first) is a subatomic particle with an electric charge of one positive fundamental unit (1. ...
In biology, the word matrix is used for the material between animal or plant cells, or generally the material (or tissue) in which more specialized structures are embedded, and also specifically for one part of the mitochondrion. ...
The electron transfer chain (also called the electron transport chain, or simply electron transport), is a series of protein complexers and lipid messengers spanning the inner mitochondrial membrane that accepts electrons from electron donors such as NADH or succinate, shuttles these electrons from within the mitochondrial matrix across the inner...
Coenzyme Q (CoQ), also known as ubiquinone or ubiquinol, is a biologically active quinone with an isoprenoid side chain, related in structure to vitamin K and vitamin E. // History Coenzyme Q was first discovered in 1957 by professor F. L. Crane and colleagues at the University of Wisconsin Enzyme Institute. ...
In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule (the oxidant, also called the hydrogen donor or electron donor) to another (the reductant, also called the hydrogen acceptor or electron acceptor). ...
NADH dehydrogenase NADH dehydrogenase (EC 1. ...
In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule (the oxidant, also called the hydrogen donor or electron donor) to another (the reductant, also called the hydrogen acceptor or electron acceptor). ...
Succinate - coenzyme Q reductase also called succinate dehydrogenase is an enzyme complex found in the matrix part of the inner mitochondrial membrane. ...
Cytochromes are generally membrane-bound proteins that contain heme groups and carry out electron transport or catalyse reductive/oxidative reactions. ...
In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule (the oxidant, also called the hydrogen donor or electron donor) to another (the reductant, also called the hydrogen acceptor or electron acceptor). ...
Intermembrane Space of Mitochondria
Because of channels in the outer membrane of the mitochondria, the content of the intermembrane space is similar to that of the content of the cytoplasm. Cross-section of a mitochondrion, showing: (1) inner membrane, (2) outer membrane, (3) cristae, (4) matrix The outer membrane refers to the outside membrane of an organelle which surrounds the rest of the organelle components. ...
As electrons move down the proteins in the electron transport chain, the electrons lose energy to bring H+ ions from the mitochondrial matrix into the intermembrane space. As a concentration gradient of hydrogen ions forms, a protein called ATP synthase harnesses the potential energy of these ions and starts chemiosmosis, where the H+ ions reenter the matrix via this enzyme bound to the cristae (folds of the inner membrane). ADP and a phosphate group are combined to form ATP. The Electron Transport Chain. ...
In biology, the word matrix is used for the material between animal or plant cells, or generally the material (or tissue) in which more specialized structures are embedded, and also specifically for one part of the mitochondrion. ...
General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ...
// An ion is an atom or a group of atoms (a chemical substance), or subatomic particle, with a net electric charge. ...
A representation of the 3D structure of myoglobin, showing coloured alpha helices. ...
An ATP synthase (EC 3. ...
The Chemiosmotic Hypothesis is the proposal in 1961, by Peter D. Mitchell, that the mitochondrion functioned as a kind of electrochemical capacitor, using the energy of NADH and FADH2 to create a proton gradient across the mitochondrial membrane and that this energy was used by a reversible proton pump, the...
Cristae are the infoldings of the inner membrane of a mitochondrion. ...
Adenosine 5-triphosphate (ATP) is a multifunctional nucleotide primarily known in biochemistry as the molecular currency of intracellular energy transfer. ...
Intermembrane Space of Chloroplast The intermembrane space of the chloroplast is extremely small, somewhere from 10-20 nm thick. The inside of a chloroplast Chloroplasts are organelles found in plant cells and eukaryotic algae that conduct photosynthesis. ...
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