In pharmacology, an inverse agonist is an agent which binds to the same receptor binding-site as an agonist for that receptor but exerts the opposite pharmacological effect. This is the case for certain types of receptors (e.g. certain histamine receptors / GABA receptors) which have intrinsic activity without the acting of a ligand upon them, which is also referred to as 'constitutive activity'. Pharmacology (in Greek: pharmacon (φάρμακον) is drug, and logos (λόγος) is science) is the study of how chemical substances interact with living systems. ... Receptor may refer to: In telecommunication, a receiver. ... Agonists An agonist is a substance that binds to a receptor and triggers a response by the cell. ...

One particular example is R015-4513 which the inverse agonist of the benzodiazepine class of drugs (such as Xanax and Valium). R015-4513 and the benzodiazepines both utilize the same GABA binding site on neurons, yet R015-4513 has the opposite effect, producing severe anxiety rather than the sedative effect the benzodiazepines. Benzodiazepine tablets The benzodiazepines are a class of drugs with hypnotic, anxiolytic, anticonvulsant, amnestic and muscle relaxant properties. ... Alprazolam, is an anxiolytic benzodiazepine used to treat anxiety disorders. ... Diazepam, brand names: Valium, Seduxen, in Europe Apozepam, is a 1,4-benzodiazepine derivative, which possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. ... Benzodiazepine tablets The benzodiazepines are a class of drugs with hypnotic, anxiolytic, anticonvulsant, amnestic and muscle relaxant properties. ... Benzodiazepine tablets The benzodiazepines are a class of drugs with hypnotic, anxiolytic, anticonvulsant, amnestic and muscle relaxant properties. ...