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Encyclopedia > Iodoform
Iodoform
Iodoform
Chemical name Triiodomethane
Chemical formula CHI3
Molecular mass 393.73 g/mol
CAS number [75-47-8]
Density 4.008 g/cm3
Melting point 118 °C
Boiling point N/A °C
SMILES IC(I)I
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The compound iodoform is a yellow, crystalline, volatile substance, I3CH, having a penetrating odor (in older chemistry texts, the smell is sometimes referred to as the smell of hospitals) and sweetish taste, and analogous to chloroform. It was used in medicine as a healing and antiseptic dressing for wounds and sores around the beginning of the 20th century, though this use is now superseded by better antiseptics. Image File history File links Iodoform-chemical. ... IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... The molecular mass (abbreviated MM) of a substance, called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... Density (symbol: ρ - Greek: rho) is a measure of mass per unit of volume. ... The melting point of a solid is the temperature at which it changes state from solid to liquid. ... The boiling point of a substance is the temperature at which it can change its state from a liquid to a gas throughout the bulk of the liquid. ... The simplified molecular input line entry specification or SMILES is a specification for unambiguously describing the structure of chemical molecules using short ASCII strings. ... PEL-TWA (OSHA) 50 ppm (240 mg/m3) IDLH (NIOSH) 500 ppm Flash point non-flammable RTECS number FS9100000 Supplementary data page Structure & properties n, εr, etc. ... An antiseptic (Greek αντι, against, and σηπτικος, putrefactive) is a substance that prevents the growth and reproduction of various microorganisms (such as bacteria, fungi, protozoa, and viruses) on the external surfaces of the body. ...


Iodoform can be synthesized in the haloform reaction by the reaction of iodine and sodium hydroxide with any one of these four kinds of organics: The haloform reaction is a chemical reaction where a haloform CHX3) is produced by the multiple halogenation of a methyl ketone (a molecule containing the R-CO-CH3 group) in the presence of a base. ...

The melting point of the compound is 119 degrees Celsius, and it is insoluble in water but soluble in ether or ethanol. Ketone group A ketone is either the functional group characterized by a carbonyl group linked to two other carbon atoms or a chemical compound that contains this functional group. ... R-phrases , , S-phrases , , , Flash point −39 °C Autoignition temperature 185 °C RTECS number AB1925000 Supplementary data page Structure and properties n, εr, etc. ... Ethanol, also known as ethyl alcohol or grain alcohol, is a flammable, colorless chemical compound, one of the alcohols that is most often found in alcoholic beverages. ... In chemistry, alcohol is any organic compound in which a hydroxyl group (-OH) is bound to a carbon atom, which in turn is bound to other hydrogen and/or carbon atoms. ...


Iodomoform is one of the trihalomethanes closely related with fluoroform, chloroform and bromoform. Trihalomethanes (THMs) are chemical compounds in which three of the four hydrogen atoms of methane (CH4) are replaced by halogen atoms. ... Trifluoromethane (CHF3), also known as fluoroform, is one of the haloalkanes with minor ozone depletion, as it doesnt contain any chlorine. ... PEL-TWA (OSHA) 50 ppm (240 mg/m3) IDLH (NIOSH) 500 ppm Flash point non-flammable RTECS number FS9100000 Supplementary data page Structure & properties n, εr, etc. ... Bromoform (CHBr3) is a pale yellowish liquid with a sweet odor, a halomethane similar to chloroform. ...


  Results from FactBites:
 
NTP: Abstract for TR-110 Iodoform (410 words)
Iodoform, a halogenated alkane with antiseptic and anti-infective properties, was selected for bioassay by the National Cancer Institute because of its similarity to methyl iodide, which has produced sarcomas in BD rats and to chloroform, a compound which has been found to induce hepatomas in NLC mice.
Iodoform in corn oil was administered by gavage, at either of two dosages, to groups of 50 male and 50 female animals of each species.
The high and low time-weighted average dosages of iodoform were, respectively, 142 and 71 mg/kg/day for male rats, 55 and 27 mg/kg/day for female rats, and 93 and 47 mg/kg/day for male and female mice.
Sciencemadness Discussion Board - Powered by XMB (1198 words)
Iodoform precipitates as yellow crystalls, those are filtered after 30 minutes, washed with small ammount of water and air dryed.
On second thoughts - it looks like the properly washed iodoform is not as lachrymatory - instead this property was probably caused by intial reaction products that were present in the supernatant - I imagine iodoacetone, a close relative to the well-known lachrymator chloroacetone, was formed as a byproduct.
I made iodoform in a way, which is somewhat less wasteful on (expensive) iodine and no elemental iodine is needed.
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