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Encyclopedia > Isoflavones

A phytoestrogen that is thought of by many as useful in treating cancer. Phytoestrogens are plant compounds which have effects similar to that of estrogen, but somewhat weaker. ...


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What is Isoflavone? (2147 words)
Soy foods differ somewhat in their concentration of isoflavones, but all of the traditional soy foods, such as tofu, soy milk, tempeh and miso, are rich sources of isoflavones providing about 30 to 40 milligrams per serving.
Conjugation of isoflavones to glucuronic acid, a reaction catalyzed by one of the UDP-glucuronyltransferase isozymes, occurs on first-pass.
Isoflavone glucuronide concentrations in portal venous blood of rats are high, and older studies of sheep showed that intestinal epithelia had a higher capacity for glucuronidation of equol than hepatocytes.
Soy Isoflavones, Linus Pauling Institute's Micronutrient Information Center (3722 words)
The biological effects of soy isoflavones are strongly influenced by their metabolism, which is dependent on the activity of bacteria that colonize the human intestine (2).
Isoflavones are also known to act as antioxidants in the test tube (10), but the extent to which they contribute to the antioxidant status of humans is not yet clear.
Isoflavones are found in small amounts in a number of legumes, grains and vegetables, but soybeans are by far the most concentrated source of isoflavones in the human diet (43, 82).
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