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Encyclopedia > Isoflurane

Structural formula of isoflurane
Structural formula of isoflurane

Isoflurane (1-chloro-2,2,2-trifluoroethyl difluoromethyl ether) is a halogenated ether used for inhalation anesthesia. Together with enflurane and halothane it replaced the flammable ethers used in the pioneer days of surgery. Its use in human medicine is now starting to decline, being replaced with sevoflurane, desflurane and the intravenous anaesthetic propofol. Isoflurane is still frequently used for veterinary anaesthesia. Image File history File links Download high resolution version (1583x1045, 14 KB) Summary Chemical structure of the anaesthetic isoflurane, self made in ChemDraw and Photoshop by Ben (Benjah-bmm27) 23:01, 3 March 2006 (UTC) Licensing File links The following pages link to this file: Isoflurane User:Benjah-bmm27/Gallery... Image File history File links Download high resolution version (1583x1045, 14 KB) Summary Chemical structure of the anaesthetic isoflurane, self made in ChemDraw and Photoshop by Ben (Benjah-bmm27) 23:01, 3 March 2006 (UTC) Licensing File links The following pages link to this file: Isoflurane User:Benjah-bmm27/Gallery... A Halogenated Ether is a subcategory of a larger group of chemicals known as ethers. ... Cetacaine, a typical topical anesthetic Anesthesia (American English), also anaesthesia (British English), is the process of blocking the perception of pain and other sensations. ... Structural formula of enflurane Enflurane (2-chloro-1,1,2,-trifluoroethyl-difluomethyl ether) is a halogenated ether that was commonly used for inhalational anesthesia during the 1970s and 1980s. ... Structural formula of halothane Halothane vapour is an inhalational general anaesthetic. ... Flash point -45 °C Autoignition temperature 170 °C R/S statement RTECS number KI5775000 Supplementary data page Structure and properties n, εr, etc. ... A typical modern surgical operation For other uses, see Surgery (disambiguation). ... Sevoflurane (2, 2, 2-trifluoro-1-(trifluoromethyl) ethyl ether), also called fluoromethyl, is a halogenated ether used for induction and maintenance of general anesthesia. ... Desflurane is a highly flourinated ether used for maintenance of general anaesthesia. ... Propofol is an intravenous anesthetic agent used for the induction of general anesthesia in adult patients and pediatric patients older than 3 years of age; maintenance of general anesthesia in adult patients and pediatric patients older than 2 months of age; and intensive care unit (ICU) sedation for intubated, mechanically...


Isoflurane is always administered in conjunction with air and/or pure oxygen. Often nitrous oxide is also used. Although its physical properties means that anaesthesia can be induced more rapidly than with halothane, its pungency can irritate the respiratory system, negating this theoretical advantages conferred by its physical properties. It is usually used to maintain a state of general anesthesia that has been induced with another drug, such as thiopentone or propofol. Look up air in Wiktionary, the free dictionary. ... General Name, Symbol, Number oxygen, O, 8 Chemical series Nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless Atomic mass 15. ... This article is about nitrous oxide, or laughing gas. ... Structural formula of halothane Halothane vapour is an inhalational general anaesthetic. ... Sodium thiopental (also called sodium pentothal (™ of Abbott Laboratories), thiopental (or thiopentone) sodium) is a rapid-onset, short-acting barbiturate general anesthetic. ... Propofol is an intravenous anesthetic agent used for the induction of general anesthesia in adult patients and pediatric patients older than 3 years of age; maintenance of general anesthesia in adult patients and pediatric patients older than 2 months of age; and intensive care unit (ICU) sedation for intubated, mechanically...


A major advantage of isoflurane is that it is no longer patented, and hence very economical to use. A patent is a set of exclusive rights granted by a government to an inventor or applicant for a limited amount of time (normally maximum 20 years from the filing date, depending on extension). ...


It vaporizes readily, but is a liquid at room temperature. It is completely non-flammable.


Physical properties

Molecular weight 184.5 g/mol
Boiling point (at 1 atm): 48.5 °C
Density (at 25 °C): 1.496 g/mL
MAC : 1.15 vol %
Vapor pressure: 238 mmHg 31.7 kPa (at 20°C)
295 mmHg 39.3 kPa (at 25°C)
367 mmHg 48.9 kPa (at 30°C)
450 mmHg 60.0 kPa (at 35°C)
Blood:Gas Partition coefficient: 1.4
Oil:Gas Partition coefficient: 98

  Results from FactBites:
 
Forane (Isoflurane) drug indications and dosage - prescription drugs and medications at RxList (587 words)
FORANE (isoflurane, USP) may be used for induction and maintenance of general anesthesia.
Induction with isoflurane in oxygen or in combination with oxygen-nitrous oxide mixtures may produce coughing, breath holding, or laryngospasm.
The level of blood pressure during maintenance is an inverse function of isoflurane concentration in the absence of other complicating problems.
Isoflurane - Wikipedia, the free encyclopedia (186 words)
Isoflurane (1-chloro-2,2,2-trifluoroethyl difluoromethyl ether) is a halogenated ether used for inhalation anesthesia.
Isoflurane is still frequently used for veterinary anaesthesia.
Isoflurane is always administered in conjunction with air and/or pure oxygen.
  More results at FactBites »

 

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