Isothiocyanate is the chemical group -N=C=S, formed by substituting sulfur for oxygen in the isocyanate group. Allyl isothiocyanate is also called mustard oil. A chemical substance is any material substance used in or obtained by a process in chemistry: A chemical compound is a substance consisting of two or more chemical elements that are chemically combined in fixed proportions. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless Atomic mass 14. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Atomic mass 12. ... General Name, Symbol, Number sulfur, S, 16 Chemical series nonmetals Group, Period, Block 16, 3, p Appearance lemon yellow Atomic mass 32. ... General Name, Symbol, Number sulfur, S, 16 Chemical series nonmetals Group, Period, Block 16, 3, p Appearance lemon yellow Atomic mass 32. ... General Name, Symbol, Number oxygen, O, 8 Chemical series nonmetals Group, Period, Block 16, 2, p Appearance colorless Atomic mass 15. ... Isocyanate is the chemical group of atoms -N=C=O (1 nitrogen, 1 carbon, 1 oxygen), as opposed to cyanate, -O-C≡N, which is formed from cyanogen in the normal -ate manner. ... H2C=CH-CH2- --- This is allyl carbon chain CH2=CH- --- This is vinyl carbon chain The link below gives a better understanding of allyl carbon. ... The term mustard oil is used for two different oils that are made from mustard seeds: a fatty oil resulting from pressing the seeds, an essential oil resulting from grinding the seeds, mixing them with water, and extracting the resulting volatile oil by distillation. ...
In one embodiment of the current invention, the isothiocyanate for use in the current invention is sulforaphane, or a derivative thereof.
Sulforaphane (4-methylsulfinylbutyl isothiocyanate or (-)-1-isothiocyanato-4(R)-(methylsulfinyl) butane) and sulforaphene (4-methylsulfinylbutenyl isothiocyanate) and their cognate glucosinolates (glucoraphanin and glucoraphenin, respectively), are known to be produced by plants, such as hoary cress, radish and other plants (Mislow et al., J. Am.
In another embodiment, the known modulators for use in the assay of the current invention are isothiocyanate, sulforaphane, sulforaphene, erysolin, erucin, iberin, alyssin, berteroin, iberverin, cheirolin, 5-methylsulfinylpentyl isothiocyanate, 6-hexylsulfinyl isothiocyanate, 7-methylsulfinylheptyl isothiocyanate, 8-methylsulfinyloctyl isothiocyanate, 9-methylsulfinylnonyl isothiocyanate, 10-methylsulfinyldecyl isothiocyanate, phenylethyl isothiocyanate, 4-(.alpha.-L-rhamnopyranosyloxy)benzyl isothiocyanate, 3-(.alpha.-L-rhamnopyranosyloxy)benzyl isothiocyanate, 2-(.alpha.-L-rhamnopyranosyloxy)benzyl isothiocyanate, 4-(4'-O-acetyl-.alpha.-L-rhamnopyranosyloxy)benzyl isothiocyanate or a derivative thereof.
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