Prince Joao of Portugal (June 3, 1537 - January 2, 1554) (in English: John) was the eighth son of King John III of Portugal by his wife Catherine of Habsburg, (princess of Spain) daughter of Philip of Flanders and Joanna of Castile. June 3 is the 154th day of the year in the Gregorian calendar (155th in leap years), with 211 days remaining. ... Events January 6 - Alessandro de Medici assassinated August 25 - The Honourable Artillery Company, the oldest surviving regiment in the British Army, and the second most senior, was formed. ... January 2 is the 2nd day of the year in the Gregorian Calendar. ... Events February 12 - After claiming the throne of England the previous year, Lady Jane Grey is beheaded for treason alongside her husband. ... The English language is a West Germanic language that originates in England. ... John III of Portugal John III of Portugal, the Pious, (Portuguese João III) (June 6, 1502 – June 11, 1557) was the fifteenth king of Portugal. ... Catherine of Austria, of the Habsburg family, princess of Spain, born a daughter of Philip, Archduke, Lord of Flanders etc and Joanna of Castile, as such Archduchess of Austria, Infanta of Castile, Princess of Burgundy and Flanders, sister of King of Aragon and Roman Emperor, etc. ...

João was born in June 3, 1537 in Évora and became the heir to the throne of Portugal in 1539. He survived his four older brothers that died in childhood, but was a sickly teenager. The successive inter-marriages between the houses of Spain and Portugal had probably some responsibility on his ill health. In 1552 he married Joan of Habsburg (princess of Spain), his direct cousin, through both paternal and maternal line, daughter of his paternal aunt Isabel of Portugal and of his maternal uncle Emperor Charles V. June 3 is the 154th day of the year in the Gregorian calendar (155th in leap years), with 211 days remaining. ... Events January 6 - Alessandro de Medici assassinated August 25 - The Honourable Artillery Company, the oldest surviving regiment in the British Army, and the second most senior, was formed. ... Évora is both a town and a district in eastern Portugal. ... Events May 30 - In Florida, Hernando de Soto lands at Tampa Bay with 600 soldiers with the goal to find gold. ... Events April - War between Henry II of France and Emperor Charles V. Henry invades Lorraine and captures Toul, Metz, and Verdun. ...

João died of what the sources refer to as consumption (tuberculosis) on January 2, 1554. Eighteen days later, a posthumous son was born from his marriage: the future king Sebastian I of Portugal. His death at the age of only sixteen was the beginning of the succession problem in Portugal that would end in the loss of independence to Spain in 1580. Tuberculous lungs show up on an X-ray image Tuberculosis is an infection with the bacterium Mycobacterium tuberculosis, which most commonly affects the lungs (pulmonary TB) but can also affect the central nervous system (meningitis), lymphatic system, circulatory system (miliary TB), genitourinary system, bones and joints. ... January 2 is the 2nd day of the year in the Gregorian Calendar. ... Events February 12 - After claiming the throne of England the previous year, Lady Jane Grey is beheaded for treason alongside her husband. ... Sebastião I (January 20, 1554 - August 4, 1578) was a King of Portugal. ... Events March 1 - Michel de Montaigne signs the preface to his most significant work, Essays. ...