Joseph L. Goldstein (b. April 18, 1940) from Kingstree, South Carolina is a biochemist and geneticist, and a pioneer in the study of cholesterol metabolism. In 1985 he received the Nobel Prize in Physiology or Medicine (together with Michael S. Brown) for his research on the metabolism of LDL, and has won numerous other awards for his contributions related to genetic diseases. April 18 is the 108th day of the year in the Gregorian calendar (109th in leap years). ... 1940 was a leap year starting on Monday (link will take you to calendar). ... Williamsburg County Courthouse, Designed by Robert Mills Kingstree, South Carolina Kingstree is a town located in Williamsburg County, South Carolina. ... Biochemistry is the chemistry of life. ... Genetics (from the Greek genno γεννώ= give birth) is the science of genes, heredity, and the variation of organisms. ... 1985 is a common year starting on Tuesday of the Gregorian calendar. ... List of Nobel Prize laureates in Physiology or Medicine from 1901 to the present day. ... Dr. Michael S. Brown (b. ... A disease is any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. ...
Joseph Leonard Goldstein, the only son of Isadore E. and Fannie (Albert) Goldstein, was born on April 18, 1940, in Sumter, South Carolina.
During this process, Goldstein and Brown were able to follow the manner inwhich the cells obtained cholesterol, and identify the process of cholesterolextraction from the lipoproteins in the serum of the culture medium, specifically LDLs.
Goldstein's and Brown's research illuminating the activity of LDL receptors and their function in the management of cholesterol levels has had far-reaching effects.
JosephL. Goldstein was born on April 18, 1940, in Sumter, South Carolina, the only son of Isadore E. and Fannie Alpert Goldstein.
After receiving the M.D. degree in 1966, Goldstein moved to Boston where he was an Intern and Resident in Medicine at the Massachusetts General Hospital (1966-68).It was at the Massachusetts General Hospital that Goldstein first met and developed a friendship with Michael S. Brown, his long-term scientific collaborator.
In Seattle, Goldstein initiated and completed a population genetic study to determine the frequency of the various hereditary lipid disorders in an unselected population of heart attack survivors.
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