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The juxtaglomerular apparatus is a renal structure consisting of the macula densa, mesangial cells, and juxtaglomerular cells. Juxtaglomerular cells (JG cells, also known as granular cells) are the site of renin secretion. Human kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ...
In the kidney, the macula densa is an area of closely packed specialized cells lining the distal convoluted tubule where it lies next to the glomerular vascular pole. ...
Mesangial cells are specialized cells around blood vessels in the kidneys. ...
The juxtaglomerular cells are specialized cells that stimulate the secretion of the adrenal hormone aldosterone and play a major role in renal autoregulation, the kidneys self-governance. ...
Renin, also known as angiotensinogenase, is a circulating enzyme (EC 3. ...
The JG cells are found in the afferent arterioles of the glomerulus and act as an intra-renal pressure sensor. Lowered pressure leads to secretion of renin which acts to increase systemic blood pressure via the renin-angiotensin system. Glomerulus refers to two unrelated structures in the body, both named for their globular form. ...
Renin, also known as angiotensinogenase, is a circulating enzyme (EC 3. ...
Schematic depicting how the RAAS works. ...
The macula densa senses fluid flow rate as well as sodium chloride concentration in the distal tubule of the kidney and secretes a locally active (paracrine) vasopressor which acts on the adjacent afferent arteriole to decrease GFR. Mesengial cells regulate the blood flow in the glomerulus. They monitor the sodium and chloride levels in the distal convoluted tubules. If the amount of these ions is more, it will imply that the kidney does not have enough time to reabsorb or GFR (glomerular filtration rate) is too high. They communicate with the afferent arteriole and will cause vasoconstriction; decreasing the blood flow, subsequently decreasing the GFR.
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| Urinary system - Kidney - edit | | Renal capsule | Renal cortex | Renal medulla (Renal sinus, Renal pyramids) | Renal calyx | Renal pelvis | | Nephron - Renal corpuscle (Glomerulus, Bowman's capsule) → Proximal tubule → Loop of Henle → Distal convoluted tubule → Collecting ducts Juxtaglomerular apparatus (Macula densa, Juxtaglomerular cells) For the unrelated Jesuit university in Chestnut Hill, see Boston College. ...
The urinary system is the organ system that produces, stores, and carries urine. ...
Human kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ...
The renal capsule is a tough fibrous layer surrounding the kidney and covered in a thick layer of perinephric adipose tissue. ...
The renal cortex is the outer portion of the kidney between the renal capsule and the renal medulla. ...
The renal medulla is the innermost part of the kidney. ...
The renal sinus is a cavity within the kidney which is occupied by the renal pelvis, renal calices, blood vessels, nerves and fat. ...
Renal pyramids are cone-shaped tissues of the kidney. ...
A calyx is a part in the kidney. ...
The renal pelvis represents the dilated proximal part of the ureter. ...
Nephron of the kidney A nephron is the basic structural and functional unit of the kidney. ...
A renal corpuscle is the initial filtering component of a nephron in the kidney. ...
Glomerulus refers to two unrelated structures in the body, both named for their globular form. ...
Bowmans Capsule is a blind sac at the beginning of a the tubular component of a nephron in the mammalian kidney. ...
In the kidney, the loop of Henle is the portion of the nephron that leads from the proximal convoluted tubule to the distal convoluted tubule. ...
Kidney nephron The distal convoluted tubule (DCT) is a portion of kidney nephron between the loop of Henle and the collecting duct system. ...
The collecting duct system of the kidney consists of: The connecting tubule The cortical collecting duct The medullary collecting duct Categories: | ...
In the kidney, the macula densa is an area of closely packed specialized cells lining the distal convoluted tubule where it lies next to the glomerular vascular pole. ...
The juxtaglomerular cells are specialized cells that stimulate the secretion of the adrenal hormone aldosterone and play a major role in renal autoregulation, the kidneys self-governance. ...
Renal circulation - Renal artery → Interlobar arteries → Arcuate arteries → Cortical radial arteries → Afferent arterioles → Glomerulus → Efferent arterioles → Vasa recta → Arcuate vein → Renal vein Grays Fig. ...
Human kidneys viewed from behind with spine removed The renal arteries normally arise off the abdominal aorta and supply the kidneys with blood. ...
The afferent arterioles are a group of blood vessels that supply the nephrons in many excretory systems. ...
The glomerulus is a capillary bed found surrounded by the Bowmans capsule of the nephron in the vertebrate kidney. ...
The Efferent arterioles are a group of blood vessels that are part of the urinary system of many animals. ...
A nephron, the vasa recta is labelled arteria recta The vasa recta is a loop of the renal circulation that surrounds the Loop of Henle, part of the nephron in the medulla of the kidney. ...
Kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ...
| | Renal physiology | | Filtration - Ultrafiltration | Countercurrent exchange Hormones effecting filtration - Antidiuretic hormone (ADH) | Aldosterone | Atrial natriuretic peptide Renal physiology is the study of the physiology of the kidneys. ...
In chemistry, alchemy and water treatment, filtration is the process of using a filter to mechanically separate a mixture. ...
Ultrafiltration (UF) is a pressure-driven membrane process for purifying and concentrating macromolecular (10^3 - 10^6 Da) solutions, especially protein solutions. ...
Countercurrent exchange is a mechanism used to transfer some component of a fluid from one flowing current of fluid to another across a permeable barrier between them. ...
Antidiuretic hormone (ADH), or arginine vasopressin (AVP), is a peptide hormone produced by the hypothalamus, and stored in the posterior part of the pituitary gland. ...
Aldosterone is a steroid hormone synthesized from cholesterol by the enzyme aldosterone synthase. ...
Atrial natriuretic factor (ANF), atrial natriuretic peptide (ANP) or atriopeptin, is a polypeptide hormone involved in the homeostatic control of body water and sodium. ...
Endocrine - Renin | Erythropoietin (EPO) | Calcitriol (Active vitamin D) | Prostaglandins The endocrine system is a control system of ductless endocrine glands that secrete chemical messengers called hormones that circulate within the body via the bloodstream to affect distant organs. ...
Renin, also known as angiotensinogenase, is a circulating enzyme (EC 3. ...
Erythropoietin Erythropoietin (or EPO) is a glycoprotein hormone that is a growth factor for erythrocyte (red blood cell) precursors in the bone marrow. ...
Vitamin D is a fat soluble vitamin that contributes to the maintenance of normal levels of calcium and phosphorus in the bloodstream. ...
Chemical structure of prostaglandin E1 (PGE1). ...
| | Assessing Renal function / Measures of dialysis | | Glomerular filtration rate | Creatinine clearance | Renal clearance ratio | Urea reduction ratio | Kt/V | Standardized Kt/V | Hemodialysis product | |