Kikuchi disease (histiocytic necrotizing lymphadenitis) is a rare, non-cancerous enlargement of the lymph nodes: the diagnosis can be confirmed by lymph node biopsy. Structure of the lymph node. ...

Kikuchi disease has been reported in association with infections with Epstein-Barr virus, human herpesvirus 6, toxoplasmosis, and Human T-lymphotropic virus 1. The Epstein-Barr virus (EBV), also called Human herpesvirus 4 (HHV-4), is a virus of the herpes family (which includes Herpes simplex virus and Cytomegalovirus), and is one of the most common viruses in humans. ... Genera Subfamily Alphaherpesvirinae    Simplexvirus    Varicellovirus    Mardivirus    Iltovirus Subfamily Betaherpesvirinae    Cytomegalovirus    Muromegalovirus    Roseolovirus Subfamily Gammaherpesvirinae    Lymphocryptovirus    Rhadinovirus Unassigned    Ictalurivirus The Herpesviridae are a family of DNA viruses that cause diseases in humans and animals. ... Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma in adults and may also be involved in certain demyelinating diseases. ...

For other causes of lymph node enlargement see lymphadenopathy. Lymphadenopathy is swelling of one or more lymph nodes. ...