| Patent 6,521,596 (4704 words) |
 | The purified peptide is pH- and temperature-stable and its amino acid composition indicates the presence of lanthionine and.beta.-methyllanthionine. |
| In the place of expected serines and threonines were the lanthionine and.beta.-methyllanthiones; other residues were apparently dehydrated it thus became clear that the mature nisin molecule was the result of posttranslational modifications, thereby prompting a search for these otherwise unknown processing enzymes began. |
| Both lanthionine and methyllanthionine are expected to be suitable for cleavage from protein with the Edman procedure. |
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