Boone, a great-nephew of Daniel Boone, graduated from the medical school of Transylvania University in Lexington, Kentucky and arrived in Chicago in 1835. He helped organize the Cook County Medical Board and served as the organization's first secretary. Boone had amedical practice with Charles V. Dyer. He was elected the first president of the Chicago Medical Society in 1850.
He was elected mayor on an anti-immigrant platform. Although Boone won, there were claims that the German and Irish immigrants in Bridgeport, which was not yet a part of the city, voted against Boone. Boone also claimed that scripture provided the basis for slavery
In his first year in office, he established the first Chicago police force under Luther Nichols. He also proposed an ordinance which would close taverns on Sundays and raise the cost of liquor licenses by 600%. Many saw this as a means of attacking German immigrants and on April 21, the move sparked the Lager Beer Riot after several tavern owners were arrested for selling beer on a Sunday.
Although Boone won, there were claims that the votes of German and Irish immigrants in Bridgeport, which was not yet a part of the city, had not been counted.
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