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Encyclopedia > Levomethamphetamine
Levomethamphetamine
Systematic (IUPAC) name
(R)-N-methyl-1-phenyl-propan-2-amine
Identifiers
CAS number 537-46-2
ATC code  ?
PubChem 1206
Chemical data
Formula C10H15N 
Mol. mass 149.2
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life  ?
Excretion Renal
Therapeutic considerations
Pregnancy cat.

? IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... PubChem is a database of chemical molecules. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Atomic mass 12. ... General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless gas Atomic mass 14. ... The molecular mass (abbreviated MM) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ... Drug metabolism is the metabolism of drugs, their biochemical modification or degradation, usually through specialized enzymatic systems. ... The liver is an organ in vertebrates including humans. ... It has been suggested that Effective half-life be merged into this article or section. ... Excretion is the process of eliminating waste products of metabolism and other materials that are of no use. ... Kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...

Legal status

OTC The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... Over-the-counter substances, also abbreviated OTC, are drugs and other medical remedies that may be sold without a prescription and without a visit to a medical professional, in contrast to prescription only medicines (POM). ...

Routes Nasal Inhalation

Levomethamphetamine (other names: l-desoxyephedrine, l-methamphetamine, levmetamfetamine ) is the l- stereoisomer of methamphetamine, a sympathomimetic vasoconstrictor which is the active ingredient used in some over-the-counter nasal decongestants. The common brand-name for levmetamfetamine in the U.S. is the Vicks Inhaler. In the U.S., the name was converted to levmetamfetamine from levo-methamphetamine to lower the risk of abuse of the decongestant preparation. In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... Stereoisomerism is the arrangement of atoms in molecules whose connectivity remains the same but their arrangement in space is different in each isomer. ... This article is about the psychostimulant, d-methamphetamine. ... Sympathomimetics are a class of drugs whose properties mimic those of a stimulated sympathetic nervous system. ... Vasoconstriction is the constriction of blood vessels, in other words, when the lumen narrows. ... A decongestant is a broad class of drugs designed to symptomatically treat ailments affecting the respiratory system. ... Motto: (traditional) In God We Trust (official, 1956–present) Anthem: The Star-Spangled Banner Capital Washington, D.C. Largest city New York City Official language(s) None at the federal level; English de facto Government Federal Republic  - President George W. Bush (R)  - Vice President Dick Cheney (R) Independence - Declared - Recognized...


Chemistry

Levomethamphetamine mimicks the sympathetic nervous system but is not thought to be nearly as addictive or centrally active as the d- isomer of methamphetamine (dextro-methamphetamine, d-methamphetamine, d-desoxyephedrine, etc.) and only exerts vasoconstricting effects used for decongestion. Grays FIG. 838– The right sympathetic chain and its connections with the thoracic, abdominal, and pelvic plexuses. ... A diagram showing the CNS: 1. ... Stereoisomerism is the arrangement of atoms in molecules whose connectivity remains the same but their arrangement in space is different in each isomer. ... Vasoconstriction is the constriction of blood vessels, in other words, when the lumen narrows. ...


Side Effects

Common side effects include muscle tremor and stomach cramps. Other side effects include hypertension and tachycardia. Fred Ward as Earl Bassett in the 1990 film Tremors. ... A cramp is an unpleasant sensation caused by contraction, usually of a muscle. ... For other forms of hypertension, see Hypertension (disambiguation). ... This article or section does not cite its references or sources. ...


Recreational Use

Although levo-methamphetamine is only very mildly centrally active (unlike dextro-methamphetamine, which acts mainly on the central nervous system), many recreational drug users abuse the inhaler preparation by cracking open the inhaler and then swallowing the cotton inside (as the cotton is soaked in levo-methamphetamine.) This gives the user a very mild "speedy" effect with a mild energy boost, similar to that of ephedrine or pseudoephedrine. Sometimes uncomfortability and displesant feelings can arise by ingesting the cotton, since the cotton is also soaked in menthol and camphor. Both menthol and camphor are analgesics and can be possibly lethal at high doses. A diagram showing the CNS: 1. ... This article is about the psychostimulant, d-methamphetamine. ... Recreational drug use is the use of psychoactive drugs for recreational purposes rather than for work, medical or spiritual purposes, although the distinction is not always clear. ... Ephedrine (EPH) is a sympathomimetic amine similar in structure to the synthetic derivatives amphetamine and methamphetamine. ... Pseudoephedrine (commonly abbreviated as PSE) is a sympathomimetic amine commonly used as a decongestant. ... Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. ... R-phrases 11-20/21/22-36/37/38 S-phrases 16-26-36 RTECS number EX1260000 (R) EX1250000 (S) Supplementary data page Structure and properties n, εr, etc. ... Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. ... R-phrases 11-20/21/22-36/37/38 S-phrases 16-26-36 RTECS number EX1260000 (R) EX1250000 (S) Supplementary data page Structure and properties n, εr, etc. ...



 

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