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Dimeric lipoprotein lipase is bound to triglyceride-rich plasma lipoproteins. (348 words) |
 | To analyze the distribution pattern of lipoprotein lipase dimers among lipoprotein classes, a specific ELISA was used and gel filtration was performed in pre- and postheparin plasma from five subjects with triglyceride ranging from 69 to 522 mg/dl. |
| In conclusion in pre- and postheparin samples most of the lipoprotein lipase dimers are associated with very low density lipoproteins when ex vivo lipolytic activity is inhibited, which supports the hypothesis that, in vivo, lipoprotein lipase may affect the receptor-mediated removal of these particles. |
| Moreover, it suggests that the association between lipoprotein lipase and cholesterol-rich lipoproteins might be an ex vivo phenomenon due to lack of inhibition of lipolytic activity. |
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Lipase - Wikipedia, the free encyclopedia (647 words) |
| A lipase is a water-soluble enzyme that catalyzes the hydrolysis of ester bonds in water–insoluble, lipid substrates. |
| Lipases are ubiquitous throughout living organisms, and genes encoding lipases are even present in certain viruses. |
| Lipoprotein lipase deficiency is caused by mutations in the gene encoding lipoprotein lipase [1]. |
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