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In 1997, Luger and her colleagues used x-ray crystallography to reveal the structure of a core chromatin particle with unprecedented detail.
Karolin Luger is investigating the structural biology of the nucleosome, the fundamental packaging unit of DNA in all eukaryotic cells that regulates gene transcription.
Luger hopes to refine the overall view of chromatin's architecture by understanding how the nucleosome interfaces with the cellular machinery based on sequence variations in its own proteins or interactions with outside molecules.
Luger, George F., Lewis, Joseph A., and Stern, Carl "Problem Solving as Model Refinement: Towards a Constructivist Epistemology" In Brain, Behavior, and Evolution, Winter 2001.
Luger, G.F. (with Johnson, P., Stern, C., Newman, J. and Yeo, R.).
Luger, G.F. and Skinner, J.M. "A synergistic approach to reasoning for autonomous satellites." In Proceedings for NATO Conference of the Advisory Group for Aerospace Research and Development, Portugal, 1991.
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