This article is about lymphoma in humans. For the disease in dogs, cats, and ferrets, see lymphoma in animals. Lymphoma is a type of cancer that originates in lymphocytes (a type of white blood cell in the vertebrate immune system). There are many types of lymphoma. Lymphomas are part of the broad group of diseases called hematological neoplasms. The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ...
The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or diseases, as classified by the World Health Organization (WHO). ...
// C00-D48 - Neoplasms (C00-C14) Malignant neoplasms, lip, oral cavity and pharynx (C00) Malignant neoplasm of lip (C01) Malignant neoplasm of base of tongue (C02) Malignant neoplasm of other and unspecified parts of tongue (C03) Malignant neoplasm of gum (C04) Malignant neoplasm of floor of mouth (C05) Malignant neoplasm of...
// C00-D48 - Neoplasms (C00-C14) Malignant neoplasms, lip, oral cavity and pharynx (C00) Malignant neoplasm of lip (C01) Malignant neoplasm of base of tongue (C02) Malignant neoplasm of other and unspecified parts of tongue (C03) Malignant neoplasm of gum (C04) Malignant neoplasm of floor of mouth (C05) Malignant neoplasm of...
The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. ...
Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ...
Lymphoma in animals is a type of cancer defined by a proliferation of malignant lymphocytes within solid organs such as the lymph nodes, bone marrow, liver and spleen. ...
Cancer is a class of diseases or disorders characterized by uncontrolled division of cells and the ability of these to spread, either by direct growth into adjacent tissue through invasion, or by implantation into distant sites by metastasis (where cancer cells are transported through the bloodstream or lymphatic system). ...
A scanning electron microscope (SEM) image of a single human lymphocyte. ...
White Blood Cells redirects here. ...
A scanning electron microscope image of a single neutrophil (yellow), engulfing anthrax bacteria (orange). ...
Although hematological malignancies are a form of cancer, they are generally treated by specialists in hematology, although in many hospitals oncology specialists also manage these diseases. ...
In the 19th and 20th centuries the affliction was called Hodgkin's Disease, as it was discovered by Thomas Hodgkin in 1832. Colloquially, lymphoma is broadly categorized as Hodgkin's lymphoma and non-Hodgkin lymphoma (all other types of lymphoma). Scientific classification of the types of lymphoma is more detailed. Hodgkins disease is a type of lymphoma described by Thomas Hodgkin in 1832, and characterized by the presence of Reed-Sternberg cells. ...
Thomas Hodgkin (August 17, 1798 - April 5, 1866) was a British physician and considered one of the most prominent pathologists of his time and a pioneer in preventive medicine. ...
Year 1832 (MDCCCXXXII) was a leap year starting on Sunday (link will display the full calendar) of the Gregorian Calendar (or a leap year starting on Friday of the 12-day slower Julian calendar). ...
Hodgkins lymphoma, also known as Hodgkins disease, is a type of lymphoma first described by Thomas Hodgkin in 1832. ...
Non-Hodgkin lymphoma (NHL) describes a group of cancers arising from lymphocytes, a type of white blood cell. ...
Although older classifications referred to histiocytic lymphomas, these are recognized in newer classifications as of B, T or NK cell lineage. Histiocytic malignancies are rare and are classified as sarcomas.[1] B cells are lymphocytes that play a large role in the humoral immune response (as opposed to the cell-mediated immune response). ...
T cells are a subset of lymphocytes that play a large role in the immune response. ...
Natural killer cells (NK) are a type of lymphocyte (a white blood cell) and a component of nonspecific immune defense. ...
A sarcoma is a cancer of the bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. ...
Prevalence According to the U.S. National Institutes of Health, lymphomas account for about five percent of all cases of cancer in the United States, and Hodgkin's lymphoma in particular accounts for less than one percent of all cases of cancer in the United States. National Institutes of Health Building 50 at NIH Clinical Center - Building 10 The National Institutes of Health (NIH) is an agency of the United States Ministry of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research. ...
Because the lymphatic system is part of the body's immune system, patients with a weakened immune system, such as from HIV infection or from certain drugs or medication, also have a higher incidence of lymphoma. The human lymphatic system The lymphatic system is a complex network of lymphoid organs, lymph nodes, lymph ducts, lymphatic tissues, lymph capillaries and lymph vessels that produce and transport lymph fluid from tissues to the circulatory system. ...
Species Human immunodeficiency virus 1 Human immunodeficiency virus 2 Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immunodeficiency syndrome (AIDS, a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections). ...
Classification
WHO classification The WHO Classification is the latest classification of lymphoma, published by the World Health Organization in 2001.[1] It was based upon the "Revised European-American Lymphoma classification" (REAL). WHO redirects here. ...
This classification attempts to classify lymphomas by cell type, i.e. the normal cell type that most likely resembles the tumor. They are classified in three large groups: the B cell tumors, the T cell and natural killer cell tumors, Hodgkin lymphoma, and other less common groups: (ICD-O codes are provided where available). B cells are lymphocytes that play a large role in the humoral immune response (as opposed to the cell-mediated immune response). ...
T cells are a subset of lymphocytes that play a large role in the immune response. ...
Natural NK cells are cytotoxic; small granules in their cytoplasm contain special proteins such as perforin and proteases known as granzymes. ...
Hodgkins disease is a type of lymphoma described by Thomas Hodgkin in 1832, and characterized by the presence of Reed-Sternberg cells. ...
The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. ...
Mature B cell neoplasms
 DNA-microarray analysis of Burkitt's lymphoma and diffuse large B-cell lymphoma (DLBCL) showing differences in gene expression patterns. Colors indicate levels of expression; green indicates genes that are overexpressed in normal cells compared to lymphoma cells and red indicates genes that are overexpressed in lymphoma cells compared to normal cells. Image File history File links Download high-resolution version (1914x1398, 707 KB) Summary Public domain image from cancer. ...
Image File history File links Download high-resolution version (1914x1398, 707 KB) Summary Public domain image from cancer. ...
Chronic lymphocytic leukemia (also known as chronic lymphoid leukemia or CLL), is a type of leukemia, or cancer of the white blood cells (lymphocytes). ...
Small cell lymphoma (or small lymphocytic lymphoma) is a type of follicular B-cell lymphoma. ...
It has been suggested that this article or section be merged into Leukemia. ...
Waldenström macroglobulinemia (WM) is cancer involving a subtype of white blood cells called lymphocytes. ...
Splenic marginal zone lymphoma is an indolent lymphoma recognized by the World Health Organization. ...
Plasma cells (also called plasma B cells or plasmocytes) are cells of the immune system that secrete large amounts of antibodies. ...
Multiple myeloma (also known as MM, myeloma, plasma cell myeloma, or as Kahlers disease after Otto Kahler) is a type of cancer of plasma cells which are immune system cells in bone marrow that produce antibodies. ...
Plasmacytoma refers to a malignant monoclonal plasma cell tumor growing either in bone or soft tissue. ...
MALT lymphoma is a form of non-Hodgkin lymphoma (NHL) involving the mucosa-associated lymphoid tissue, usually of the stomach. ...
Follicular lymphoma (FL) is the most common of the indolent non-Hodgkins lymphomas. ...
Mantle cell lymphoma (MCL) is one of the rarer of the non-Hodgkins lymphomas, comprising about 6% of NHL cases. ...
B-cell lymphoma is a type of non-Hodgkin lymphoma affecting B cells. ...
The introduction to this article provides insufficient context for those unfamiliar with the subject matter. ...
Primary effusion lymphoma (PEL) is a malignancy of B cells that is caused by Kaposis sarcoma-associated herpesvirus (KSHV). ...
Burkitts lymphoma (or Burkitts tumor, or Malignant lymphoma, Burkitts type) is a cancer of the lymphatic system (in particular, B lymphocytes). ...
Lymphomatoid granulomatosis is a neoplastic disease. ...
Mature T cell and natural killer (NK) cell neoplasms T-cell-prolymphocytic leukemia (T-PLL) is a mature T-cell leukemia with aggressive behavior and predilection for blood, bone marrow, lymph nodes, liver, spleen, and skin involvement. ...
// Proliferation of large granular lymphocytes (LGLs), LGL leukemia, Tγ-lymphoproliferative disorder, T-cell chronic lymphocytic leukemia[1] 9831/3[1] T-cell large granular lymphocyte leukemia is a disease that exhibits a unexplained, chronic (> 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood. ...
Mycosis Fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides, is a rare form of non-Hodgkins lymphoma. ...
Sézarys disease (or Sézary syndrome) is a type of cutaneous lymphoma characterized by Albert Sézary. ...
Lymphomatoid papulosis (LyP) is a rare skin disorder. ...
Hodgkin lymphoma -
- Nodular lymphocyte-predominant Hodgkin lymphoma
- Classical Hodgkin lymphoma
- Nodular sclerosis
- Mixed cellularity
- Lymphocyte-rich
- Lymphocyte depleted or not depleted
Immunodeficiency-associated lymphoproliferative disorders -
- Associated with a primary immune disorder
- Associated with the Human Immunodeficiency Virus (HIV)
- Post-transplant
- Associated with Methotrexate therapy
Species Human immunodeficiency virus 1 Human immunodeficiency virus 2 Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immunodeficiency syndrome (AIDS, a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections). ...
Working formulation The Working Formulation, published in 1982, is primarily descriptive. It is still occasionally used, but has been superseded by the WHO classification, above.
Low grade Chronic lymphocytic leukemia (also known as chronic lymphoid leukemia or CLL), is a type of leukemia, or cancer of the white blood cells (lymphocytes). ...
Lymph nodes are components of the lymphatic system. ...
Large cell is a term used in oncology. ...
High grade Lymphoblasts are immature white blood cells which typically differentiate to form normal white blood cells but which proliferate uncontrollably in leukemia. ...
Burkitts lymphoma (or Burkitts tumor, or Malignant lymphoma, Burkitts type) is a cancer of the lymphatic system (in particular, B lymphocytes). ...
Miscellaneous Mycosis Fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides, is a rare form of non-Hodgkins lymphoma. ...
A Histiocyte is a cell that is part of the human immune system. ...
Plasmacytoma refers to a malignant monoclonal plasma cell tumor growing either in bone or soft tissue. ...
Other classification systems The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. ...
Internet Archive headquarters is in the Presidio, a former US military base in San Francisco. ...
A dead link or broken link is a link on the world wide web that points to a webpage or server that is permanently unavailable. ...
The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ...
Diagnosis, etiology, staging, prognosis, and treatment See separate links to Hodgkin's lymphoma and non-Hodgkin's lymphoma. Hodgkins lymphoma, also known as Hodgkins disease, is a type of lymphoma first described by Thomas Hodgkin in 1832. ...
Non-Hodgkins lymphoma is a type of cancer. ...
Genetics Enteropathy associated T-cell lymphoma (EATL) is environmentally induced as a result of the consumption of Triticeae glutens. In gluten sensitive individuals with EATL 68% are homozygotes of the DQB1*02 subtype at the HLA-DQB1 locus (serotype DQ2).[2] (See Coeliac Disease, HLA-DQ, HLA DR3-DQ2) Wheat gluten flour Triticeae glutens are seed storage proteins found in mature seeds of grass tribe Triticeae. ...
Coeliac disease or celiac disease is an autoimmune disorder of the small bowel that occurs in genetically predisposed individuals in all age groups after early infancy. ...
HLA DQ is a protein/peptide-antigen receptor and graft-versus-host disease antigen that is composed of 2 subunits DQα and DQβ. DQα and DQβ are encoded by two loci, HLA-DQA1 and HLA-DQB1 which are found in the MHC Class II (or HLA-D) region in the...
HLA DR3-DQ2 is the serotypic representation of a HLA-DRB1: DQA1 :DQB1 haplotype. ...
See also Hodgkins lymphoma, also known as Hodgkins disease, is a type of lymphoma first described by Thomas Hodgkin in 1832. ...
Non-Hodgkins lymphoma is a type of cancer. ...
Follicular lymphoma (FL) is the most common of the indolent non-Hodgkins lymphomas. ...
Burkitts lymphoma (or Burkitts tumor, or Malignant lymphoma, Burkitts type) is a cancer of the lymphatic system (in particular, B lymphocytes). ...
Mantle cell lymphoma (MCL) is one of the rarer of the non-Hodgkins lymphomas, comprising about 6% of NHL cases. ...
Endoscopic image of gastric MALT lymphoma taken in body of stomach in patient who presented with upper GI hemorrhage. ...
Cutaneous T-Cell lymphoma (CTCL) is a class of non-Hodgkins lymphoma, which is a type of cancer of the immune system. ...
Mycosis Fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides, is a rare form of non-Hodgkins lymphoma. ...
Anaplastic large cell lymphoma (ALCL) is a type of non_Hodgkin lymphoma that features in the World Health Organisation (WHO) classification of lymphomas. ...
The mucosa-associated lymphoid tissue (MALT) is the diffuse system of small concentrations of lymphoid tissue found in various sites of the body such as the gastrointestinal tract, thyroid, breast, lung, salivary glands, eye, and skin. ...
Primary CNS lymphoma is a primary intracranial tumor usually present in those with severe immunosuppression --- commonly in those with AIDS --- and represents around 20% of all cases of lymphomas in HIV infection (other types being Burkitts lymphoma and immunoblastic lymphoma). ...
BCP-1 cells are a clonal lymphoma cell line. ...
Ann Arbor staging is the staging system for lymphomas, both in Hodgkins lymphoma (previously called Hodgkins Disease) and Non-Hodgkin lymphoma (abbreviated NHL). ...
The International Prognostic Index (IPI) is a clinical tool developed by oncologists to aid in predicting the prognosis of patients with aggressive non-Hodgkins lymphoma. ...
References - ^ a b Pathology and Genetics of Haemo (World Health Organization Classification of Tumours S.). Oxford Univ Pr. ISBN 92-832-2411-6.
- ^ Al-Toma A, Verbeek WH, Hadithi M, von Blomberg BM, Mulder CJ (2007). "Survival in Refractory Coeliac Disease and Enteropathy associated T cell Lymphoma: Retrospective evaluation of single centre experience". doi:10.1136/gut.2006.114512. PMID 17470479.
A digital object identifier (or DOI) is a standard for persistently identifying a piece of intellectual property on a digital network and associating it with related data, the metadata, in a structured extensible way. ...
External links Image File history File links Broom_icon. ...
Research Foundations
Information
Societies
Statistics | Pathology: hematology (primarily D50-D77, 280-289) | RBCs/anemia/
hemoglobinopathy
(Myeloid) | nutritional anemia: Iron deficiency anemia, Plummer-Vinson syndrome, Megaloblastic anemia (Pernicious anemia)
hereditary hemolytic anemia: enzyme disorders (G6PD Deficiency, Pyruvate kinase deficiency,Triosephosphate isomerase deficiency), Thalassemia, Sickle-cell disease/trait, Hereditary spherocytosis, Hereditary elliptocytosis, Hereditary stomatocytosis acquired hemolytic anemia: Autoimmune (Warm), HUS, MAHA, PNH, PCH A renal cell carcinoma (chromophobe type) viewed on a hematoxylin & eosin stained slide Pathologist redirects here. ...
Hematology (American English) or haematology (British English) is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. ...
“Red cell†redirects here. ...
This article discusses the medical condition. ...
Hemoglobinopathy is a kind of genetic defect that results in abnormal structure of one of the globin chains of the hemoglobin molecule. ...
Myeloid cells is a subsummating term for all hemopoietic cells except the lymphoid ones (T-cells, B-cells, NK-cells, dendritic cells). ...
Iron deficiency anemia is the most common type of anemia, and the most common cause of microcytic anemia. ...
The Plummer-Vinson syndrome, also called Paterson-Kelly syndrome or sideropenic dysphagia is a disorder linked to severe, long-term iron deficiency anemia, which causes swallowing difficulty (dysphagia) due to web-like membranes of tissue growing in the throat (esophageal webs). ...
Megaloblastic anemia is an anemia (of macrocytic classification) which results from a deficiency of vitamin B12 and folic acid. ...
Pernicious anemia (also known as Biermers anaemia or Addisons anaemia or Addison-Biermer anaemia) is a form of megaloblastic anaemia due to vitamin B12 deficiency dependent on impaired absorption of vitamin B12 in the setting of atrophic gastritis, and more specifically of loss of gastric parietal cells. ...
Hemolytic anemia is anemia due to hemolysis, the abnormal breakdown of red blood cells either in the blood vessels (intravascular hemolysis) or elsewhere in the body (extravascular). ...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked recessive hereditary disease featuring nonimmune hemolytic anemia in response to a number of causes. ...
Pyruvate Kinase Deficiency is an inherited autosomal recessive disorder which affects the survival of red blood cells, causing them to break down easily. ...
Thalassemia (British spelling, thalassaemia) is an inherited autosomal recessive blood disease. ...
Sickle-cell disease is a blood disorder characterised by red blood cells that assume an abnormal, rigid, sickle shape. ...
Sickle cell trait describes the way a person can inherit some of the genes of sickle cell disease, but not develop symptoms. ...
This article is about aspects of spherocytosis specific to the hereditary form of the disorder. ...
Hereditary elliptocytosis is a blood disorder in which 50-90% of the red blood cells consist of rod forms and elliptocytes (that is, elliptical erythrocytes); often associated with a hemolytic anemia. ...
Hereditary stomatocytosis describes a number of inherited autosomal dominant human conditions which affect the red blood cell, in which the membrane or outer coating of the cell leaks sodium and potassium ions. ...
Autoimmune hemolytic anemia (AIHA) is one type of hemolytic anemias caused by excessive hemolyisis and it is identified by auto-antibodies that react with RBCs. ...
Warm Autoimmune Hemolytic Anemia (warm AIHA) is the most common of the autoimmune hemolytic diseases. ...
In medicine, Hemolytic-uremic syndrome (or haemolytic-uraemic syndrome, abbreviated HUS) is a disease characterised by microangiopathic hemolytic anemia, acute renal failure and a low platelet count (thrombocytopenia). ...
In medicine (hematology) microangiopathic hemolytic anemia (MAHA) is a subgroup of hemolytic anemia (anemia, loss of red blood cells through destruction) caused by factors in the small blood vessels. ...
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired life-threatening disease of the blood characterised by hemolytic anemia, thrombosis and red urine due to breakdown of red blood cells. ...
An autoimmune disease like paroxysmal nocturnal hemoglobinuria (PNH). ...
aplastic anemia: Acquired PRCA, Diamond-Blackfan anemia, Fanconi anemia • Sideroblastic anemia | Coagulation/platelets
(Myeloid) | coagulopathy: DIC (Congenital afibrinogenemia, Purpura fulminans) • Hemophilia (A/VII, B/IX, C/XI, XIII) • Von Willebrand disease Purpura: Henoch-Schönlein, ITP (Evans syndrome), TTP Aplastic anemia is a condition where bone marrow does not produce sufficient new cells to replenish blood cells. ...
Acquired pure red cell aplasia (or PRCA) refers to a type of anemia affecting the precursors to red blood cells but not to white blood cells. ...
Diamond-Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents in infancy. ...
Fanconi anemia (FA) is a genetic disease that affects children and adults from all ethnic backgrounds. ...
Sideroblastic anemia is caused by the abnormal production of red blood cells as part of myelodysplastic syndrome, which can evolve into hematological malignancies (especially acute myelogenous leukemia). ...
This article is about the clotting of blood. ...
A 250 ml bag of newly collected platelets. ...
Myeloid cells is a subsummating term for all hemopoietic cells except the lymphoid ones (T-cells, B-cells, NK-cells, dendritic cells). ...
This page is a candidate to be moved to Wiktionary. ...
Disseminated intravascular coagulation (DIC) is a pathological process in the body where the blood starts to coagulate throughout the whole body. ...
Purpura fulminans is a haemorrhagic condition usually associated with sepsis or previous infection. ...
Haemophilia (also spelled as hemophilia, from the Greek haima blood and philia to love[1]) is a group of hereditary genetic disorders that impair the bodys ability to control blood clotting or coagulation. ...
Haemophilia A (also spelled Hemophilia A or Hæmophilia A) is a blood clotting disorder caused by a mutation of the factor VIII gene, leading to a deficiency in Factor VIII. It is the most common hemophilia. ...
Haemophilia B (also spelled Grus, Hemophilia B or Hæmophilia B) is a blood clotting disorder caused by a mutation of the Factor IX gene. ...
A mild form of hemophilia that mainly occurs in Jews of Ashkenazi descent. ...
Factor XIII or fibrin stabilizing factor is an enzyme (EC 2. ...
Von Willebrand disease (vWD) is the most common hereditary coagulation abnormality described in humans, although it can also be acquired as a result of other medical conditions. ...
Purple discolorations on the skin caused by bleeding underneath the skin. ...
In medicine (rheumatology and pediatrics) Henoch-Schönlein purpura (HSP, also known as allergic purpura) is a systemic vasculitis characterized by prominent tissue deposition of IgA-containing immune complexes, especially in the skin and kidney. ...
Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low platelet count (thrombocytopenia) of no known cause (idiopathic). ...
Evans Syndrome is an autoimmune disease in which an individuals antibodies attack their own RBCs as well as their platelets. ...
Thrombotic thrombocytopenic purpura (TTP or Moschcowitz disease) is a rare disorder of the blood coagulation system. ...
primary hypercoagulable state: Protein C deficiency - Protein S deficiency - Antithrombin III deficiency - Factor V Leiden - Activated protein C resistance - Antiphospholipid syndrome Thrombophilia is the propensity to develop thrombosis (blood clots) due to an abnormality in the system of coagulation. ...
How to recognize Protein C deficiency ...
Protein S deficiency is a disorder associated with increased risk of thrombosis. ...
Antithrombin III deficiency is a rare hereditary disorder that generally comes to light when a patient suffers recurrent venous thrombosis and pulmonary embolism. ...
Factor V Leiden (sometimes Factor VLeiden) is the name given to a variant of human factor V that causes a hypercoagulability disorder. ...
Activated protein C resistance is a hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). ...
This article, image, template or category should belong in one or more categories. ...
other hemorrhagic conditions: Bernard-Soulier syndrome - Glanzmann's thrombasthenia - Grey platelet syndrome - May Hegglin anomaly Bernard-Soulier syndrome (BSS, named after Jean Bernard and Jean Pierre Soulier) is a rare congenital bleeding disorder characterized by thrombocytopenia and large platelets and was first described in 1948. ...
Glanzmanns thrombasthenia is an extremely rare, autosomal recessive disorder of the blood, in which the platelets lack GPIIb/IIIa. ...
Grey platelet syndrome is a rare condition caused by a reduction or absence of the platelet alpha-granules in blood platelet, or of the proteins contained in these granules. ...
Essential thrombocytosis - Thrombocytopenia | Monocytes/Macrophages
(Myeloid) | WHO-I histiocytosis (Langerhans cell histiocytosis) WHO-II/non-Langerhans-cell histiocytosis (Juvenile xanthogranuloma, Hemophagocytic lymphohistiocytosis) Essential thrombocytosis (ET, also known as essential thrombocythemia) is a rare chronic blood disorder characterized by the overproduction of platelets by megakaryocytes in the bone marrow in the absence of an alternative cause. ...
Thrombocytopenia (or -paenia, or thrombopenia in short) is the presence of relatively few platelets in blood. ...
Monocyte A monocyte is a leukocyte, part of the human bodys immune system that protects against blood-borne pathogens and moves quickly (aprox. ...
A macrophage of a mouse stretching its arms to engulf two particles, possibly pathogens Macrophages (Greek: big eaters, from makros large + phagein eat) are cells within the tissues that originate from specific white blood cells called monocytes. ...
Myeloid cells is a subsummating term for all hemopoietic cells except the lymphoid ones (T-cells, B-cells, NK-cells, dendritic cells). ...
Though histiocytosis can refer to any of several specific diseases, the term is generally used to refer to a rare blood disease that is caused by an excess of white blood cells called histiocytes. ...
This article or section is in need of attention from an expert on the subject. ...
Juvenile xanthogranuloma is a form of histiocytosis, classified as non-Langerhans cell histiocytosis,[1] or more specifically, type 2.[2] ^ Nakasu S, Tsuji A, Fuse I, Hirai H. Intracranial solitary juvenile xanthogranuloma successfully treated with stereotactic radiosurgery. J Neurooncol. ...
Hemophagocytic lymphohistiocytosis is a form of histiocytosis where there is an excess of both histiocytes and lymphocytes. ...
WHO-III/malignant histiocytic disorders (Acute monocytic leukemia, Malignant histiocytosis, Erdheim-Chester disease) Acute monocytic leukemia (AMoL, or AML-M5) is considered a type of acute myeloid leukemia. ...
Malignant histiocytosis is a hereditary disease found in the Bernese Mountain Dog characterized by histiocytic infiltration of the lungs and lymph nodes. ...
Erdheim-Chester disease (also known as Erdheim-Chester syndrome or polyostotic sclerosing histiocytosis) is a rare form of non-Langerhans-cell histiocytosis. ...
-cytosis: Monocytosis Leukocytosis is an elevation of the white blood cell count (the leukocyte count) above the normal range. ...
Monocytosis is an increase in the number of circulating monocytes. ...
-penia: Monocytopenia | Granulocytes
(Myeloid) | -cytosis: granulocytosis (Neutrophilia, Eosinophilia, Basophilia)
-penia: Granulocytopenia/agranulocytosis (Neutropenia, Kostmann syndrome) | | Other/general myeloid | Chronic granulomatous disease | | Lymphoid | -cytosis: Lymphocytosis
-penia: Lymphopenia | | Other | Asplenia/hyposplenism - Methemoglobinemia - Pancytopenia | | See also hematological malignancy and immune disorders | | Hematological malignancy histology (ICD-O 9590-9989) | | Lymphomas (9590-9759) | Hodgkin's lymphoma vs. Non-Hodgkin lymphoma - Diffuse lymphoma vs. Follicular lymphoma
B-cell lymphoma (Small cell, Primary effusion, Diffuse large, ,Burkitt's, Splenic marginal zone, MALT)
T-cell lymphoma (Cutaneous , Mycosis fungoides/Sézary's disease, Angioimmunoblastic, Anaplastic large cell, Hepatosplenic)
plasma cell (Plasmacytoma, Multiple myeloma)
Leukopenia or leukocytopenia refers to a decrease in the number of circulating white blood cells (leukocytes) in the blood. ...
Eosinophil granulocyte Basophil granulocyte Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm. ...
Myeloid cells is a subsummating term for all hemopoietic cells except the lymphoid ones (T-cells, B-cells, NK-cells, dendritic cells). ...
Leukocytosis is an elevation of the white blood cell count (the leukocyte count) above the normal range. ...
In medicine, granulocytosis is the presence in peripheral blood of an increased number of granulocytes, a category of white blood cells. ...
Neutrophilia (or neutrophil leukocytosis) is a condition where a person has a high number of neutrophil granulocytes in their blood. ...
Eosinophilia is the state of having high eosinophil granulocytes in the blood. ...
Leukopenia or leukocytopenia refers to a decrease in the number of circulating white blood cells (leukocytes) in the blood. ...
Agranulocytosis (literally meaning an increase of agranulocytes or more commonly, a lack of granulocytes) is an acute condition involving a severe and dangerous leukopenia (reduction in the number of white blood cells) in the body. ...
Neutropenia (or neutropaenia, adjective neutrop(a)enic) is a hematological disorder characterized by an abnormally low number of neutrophil granulocytes (a type of white blood cell). ...
Kostmann syndrome is a rare inherited form of neutropenia usually detected soon after birth. ...
Myeloid cells is a subsummating term for all hemopoietic cells except the lymphoid ones (T-cells, B-cells, NK-cells, dendritic cells). ...
Chronic granulomatous disease (CGD) is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly, the superoxide radical) used to kill certain ingested pathogens. ...
A scanning electron microscope (SEM) image of a single human lymphocyte. ...
Leukocytosis is an elevation of the white blood cell count (the leukocyte count) above the normal range. ...
Lymphocytosis is an increase in the number of lymphocytes in the blood. ...
Leukopenia or leukocytopenia refers to a decrease in the number of circulating white blood cells (leukocytes) in the blood. ...
Lymphopenia is the condition in which there exists an abnormally low number of lymphocytes in the blood. ...
Asplenia refers to the absence (a-) of normal spleen function and is associated with some risks. ...
Methemoglobinemia, also known as met-Hb, is a disorder characterized by the presence of a higher than normal level of methemoglobin in the blood. ...
Pancytopenia is a medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets. ...
Although hematological malignancies are a form of cancer, they are generally treated by specialists in hematology, although in many hospitals oncology specialists also manage these diseases. ...
The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. ...
Hodgkins lymphoma, also known as Hodgkins disease, is a type of lymphoma first described by Thomas Hodgkin in 1832. ...
Non-Hodgkin lymphoma (NHL) describes a group of cancers arising from lymphocytes, a type of white blood cell. ...
Diffuse lymphoma is a type of Non-Hodgkin lymphoma where there is not a detectable pattern to the tumors progression through the lymph node (in contrast to follicular lymphoma. ...
Follicular lymphoma (FL) is the most common of the indolent non-Hodgkins lymphomas. ...
B-cell lymphoma is a type of non-Hodgkin lymphoma affecting B cells. ...
Small cell lymphoma (or small lymphocytic lymphoma) is a type of follicular B-cell lymphoma. ...
Primary effusion lymphoma (PEL) is a malignancy of B cells that is caused by Kaposis sarcoma-associated herpesvirus (KSHV). ...
B-cell lymphoma is a type of non-Hodgkin lymphoma affecting B cells. ...
Burkitts lymphoma (or Burkitts tumor, or Malignant lymphoma, Burkitts type) is a cancer of the lymphatic system (in particular, B lymphocytes). ...
Splenic marginal zone lymphoma is an indolent lymphoma recognized by the World Health Organization. ...
MALT lymphoma is a form of non-Hodgkin lymphoma (NHL) involving the mucosa-associated lymphoid tissue, usually of the stomach. ...
T-cell lymphoma (in contrast to B-cell lymphoma) can refer to: Adult T-cell leukemia Cutaneous T Cell lymphoma Category: ...
Cutaneous T-Cell lymphoma (CTCL) is a class of non-Hodgkins lymphoma, which is a type of cancer of the immune system. ...
Mycosis Fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides, is a rare form of non-Hodgkins lymphoma. ...
Sézarys disease (or Sézary syndrome) is a type of cutaneous lymphoma characterized by Albert Sézary. ...
Angioimmunoblastic T-cell lymphoma (AILT) is a mature T-cell lymphoma with systemic characterized by a polymorphous lymph node infiltrate showing a marked increase in follicular dendritic cells (FDCs) and high endothelial venules (HEVs) and systemic involvement. ...
Anaplastic large cell lymphoma (ALCL) is a type of non_Hodgkin lymphoma that features in the World Health Organisation (WHO) classification of lymphomas. ...
// Hepatosplenic γδ T-cell lymphoma[1] 9716/3[1] Hepatosplenic T-cell lymphoma is a systemic neoplasm comprised of medium-sized cytotoxic T-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow. ...
Plasma cells (also called plasma B cells or plasmocytes) are cells of the immune system that secrete large amounts of antibodies. ...
Plasmacytoma refers to a malignant monoclonal plasma cell tumor growing either in bone or soft tissue. ...
Multiple myeloma (also known as MM, myeloma, plasma cell myeloma, or as Kahlers disease after Otto Kahler) is a type of cancer of plasma cells which are immune system cells in bone marrow that produce antibodies. ...
mast cell tumor (Mast-cell sarcoma, Malignant mastocytosis, Malignant histiocytosis, Langerhans cell histiocytosis) | | Immunoproliferative disorders (9760-9799) | Waldenström macroglobulinemia - Lymphomatoid granulomatosis | | Lymphoid leukemias (9800-9839) | ALL - CLL - T-cell leukemia (Adult, Large granular lymphocyte, Prolymphocytic, Acute lymphoblastic) - B-cell leukemia (Prolymphocytic) | | Myeloid leukemias (9840-9939, 9963) | AML (M2, APL/M3, AMoL/M5, Erythroleukemia/M6, AMKL/M7) - CML (CMoL, CNL, Philadelphia chromosome) - Granulocytic sarcoma | | Other leukemias (9940-9949) | Hairy cell leukemia - Aggressive NK-cell leukemia | | Myeloproliferative disease (9950-9961) | Polycythemia vera - Essential thrombocytosis - Myelofibrosis | | Other (9964-9989) | Hypereosinophilic syndrome - Post-transplant lymphoproliferative disorder - Myelodysplastic syndrome | | See also hematology and immune disorders | A mast cell tumor is a type of tumor consisting of mast cells that is found in many species of animals. ...
Mast-cell sarcoma is an aggressive[1] form of sarcoma of the mast cells. ...
In medicine, mastocytosis is a group of rare disorders of both children and adults caused by the presence of too many mast cells (mastocytes) in a persons body. ...
Malignant histiocytosis is a hereditary disease found in the Bernese Mountain Dog characterized by histiocytic infiltration of the lungs and lymph nodes. ...
This article or section is in need of attention from an expert on the subject. ...
Immunoproliferative disorders (or immunoproliferative diseases, or immunoproliferative neoplasms) are a group of conditions affecting the immune system where there is overproduction of immunoglobulins or pluripotential hemopoietic stem cell or by abnormal proliferation of primary cells. ...
Waldenström macroglobulinemia (WM) is cancer involving a subtype of white blood cells called lymphocytes. ...
Lymphomatoid granulomatosis is a neoplastic disease. ...
Lymphoid leukemia (or lymphocytic leukemia) is a type of leukemia affecting lymphoid tissue. ...
Acute lymphoblastic leukemia (ALL), also known as acute lymphocytic leukemia, is a form of leukemia, characterised by the overproduction and continuous multiplication of malignant and immature white blood cells (also known as lymphoblasts) in the bone marrow. ...
Chronic lymphocytic leukemia (also known as chronic lymphoid leukemia or CLL), is a type of leukemia, or cancer of the white blood cells (lymphocytes). ...
T-Cell Leukemia, or T-Cell ALL, A |
