I dear to suppose that the main cause of it was appendicitis which killed a lot of hunters in prehistoric times.
Indeed, the appendix is affected when both protein excess and the lack of cellulose take place, in other words, when the maincourse in menu is a roasted mammoth without vegetable garnish.
What is required is educate people and gradually change the course of agriculture and food industry if we want to have not only tasty food but also healthy people.
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