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Encyclopedia > Martin Karplus

Martin Karplus (born March 15, 1930, Vienna, Austria) is an Austrian-born U.S. chemist. He has been Theodore William Richards Professor of Chemistry at Harvard University since 1979. March 15 is the 74th day of the year in the Gregorian Calendar (75th in Leap years). ... 1930 (MCMXXX) is a common year starting on Wednesday. ... Vienna (German: Wien [viːn]; Slovenian: Dunaj, Croatian and Serbian: Beč Romanian: Viena, Hungarian: Bécs, Czech: Vídeň, Slovak: Viedeň, Romany Vidnya;) Vienna is the capital of Austria, and also one of the nine States of Austria. ... Harvard University (incorporated as The President and Fellows of Harvard College) is a private university in Cambridge, Massachusetts. ...


Education: B.A., Harvard, 1950; Ph.D., California Institute of Technology, 1953 (working with Linus Pauling). He was an NSF Postdoctoral Fellow at Oxford University (1953-55) where he worked with C. A. Coulson. The California Institute of Technology (commonly referred to as Caltech) is a private, coeducational university located in Pasadena, California, in the United States. ... Linus Carl Pauling (February 28, 1901 – August 19, 1994) was an American quantum chemist and biochemist, widely regarded as the premier chemist of the twentieth century. ... The University of Oxford, located in the city of Oxford in England, is the oldest university in the English-speaking world. ...


Dr. Karplus has made varied contributions to nuclear magnetic resonance spectroscopy, particularly to the understanding of nuclear spin-spin coupling and electron spin resonance spectroscopy. The Karplus equation descriping the correlation between coupling constants and back bone torsion angles in protein nuclear magnetic resonance spectroscopy is named after him. Nuclear Magnetic Resonance Spectroscopy most commonly known as NMR Spectroscopy is the name given to the technique which exploits the magnetic properties of nuclei. ... Overview Electron Paramagnetic Resonance (EPR) or Electron Spin Resonance (ESR) is a spectroscopic technique which detects species that have unpaired electrons, generally meaning that it must be a free radical, if it is an organic molecule, or that it has transition metal ions if it is a inorganic complex. ... In physics, a coupling constant, usually denoted g, is a number that determines the strength of an interaction. ... Pacific Northwest National Laboratorys high magnetic field (800 MHz) NMR spectrometer being loaded with a sample. ...


His current research is concerned primarily with the properties of molecules of biological interest.


External link

  • Biography at Michigan State University website

  Results from FactBites:
 
C&EN: SCIENCE & TECHNOLOGY - JACS 125 - KARPLUS EQUATION (760 words)
The Karplus equation, as it is now known, describes the relationship between the nuclear magnetic resonance (NMR) coupling constant and the dihedral angle between vicinal hydrogens (hydrogens attached to neighboring carbon atoms).
Karplus' equation quantified something a few chemists had noticed qualitatively: A proton could interact with its vicinal neighbor, and that influence varies depending on the geometry of the two protons.
Today, variations of the Karplus equation are heavily used in establishing protein structure from NMR spectra.
MSU Chemistry - Max T. Rogers Lectureship 1995 (555 words)
Karplus has made varied contributions to magnetic resonance spectroscopy, particularly to the understanding of nuclear spin-spin coupling.
Karplus has done fundamental work on the detailed theory of reactive collisions; in particular, on the development of quasiclassical procedures for the treatment of collision dynamics.
Karplus is now concerned primarily with the properties of molecules of biological interest.
  More results at FactBites »


 

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