The mean corpuscular hemoglobin concentration, or MCHC, is a measure of the concentration of hemoglobin in a red blood cell. It is reported as part of a standard complete blood count. It is diminished ("hypochromic") in microcytic anemias, and normal ("normochromic") in macrocytic anemias (due to larger cell size, though the haemoglobin amount or MCH is high, the concentration remains normal) . 3-dimensional structure of hemoglobin. ... Human red blood cells Red blood cells are the most common type of blood cell and are the vertebrate bodys principal means of delivering oxygen from the lungs or gills to body tissues via the blood. ... A complete blood count (CBC) or full blood count (FBC) is a test requested by a doctor or other medical professional that gives information about the cells in a patients blood. ... This article discusses the medical condition. ...
Because of the way automated analysers count blood cells, a very high MCHC (greater than about 370 g/L) may indicate the blood is from someone with a cold agglutination problem. This means that when their blood gets colder than 37°C it starts to clump together. This makes the machine think there are a low number of very dense red blood cells. An automated analyser is a laboratory machine designed to measure different chemicals in a number of biological samples quickly, with minimal human assistance. ... Human blood smear: a - erythrocytes; b - neutrophil; c - eosinophil; d - lymphocyte. ...
This is problem usually picked up by the laboratory before the result is reported. The blood is warmed until the cells separate from each other, and quickly put through the machine while still warm.
Meancorpuscularhemoglobin concentration (abbreviated as MCHC) is an estimate of the concentration (amount) of hemoglobin in a given number of packed red blood cells.
Hemoglobin is a substance in the blood that carries oxygen to the cells in the body from the lungs.
Hemoglobin is a substance in the blood that carries oxygen to the cells in the body.
The meancorpuscularhemoglobin concentration, or MCHC, is a measure of the concentration of hemoglobin in a red blood cell.
It is diminished ("hypochromic") in microcytic anemias, and normal ("normochromic") in macrocytic anemias (due to larger cell size, though the haemoglobin amount or MCH is high, the concentration remains normal).
Because of the way automated analysers count blood cells, a very high MCHC (greater than about 370 g/L) may indicate the blood is from someone with a cold agglutination problem.
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