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Encyclopedia > Mebendazole

This article is about a pharmaceutical drug, for the automobile brand abbreviated as MBZ, see Mercedes-Benz This article is about a pharmaceutical drug, for the automobile brand abbreviated as MBZ, see Mercedes-Benz Mebendazole (brand name Ovex®, Vermox®, Antiox® or Pripsen®) is a drug commonly used to combat pinworms, roundworms and hookworms. ... This page is about the Mercedes-Benz brand of automobiles and trucks from the DaimlerChrysler automobile manufacturer. ...

Mebendazole
Systematic (IUPAC) name
methyl [(5-benzoyl-3H-benzoimidazol-2-yl)amino]formate
Identifiers
CAS number 31431-39-7
ATC code  ?
PubChem 7847434
DrugBank APRD01086
Chemical data
Formula C16H13N3O3 
Mol. mass 295.293 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life 2.5 to 5.5 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

? Image File history File links Mebendazole. ... IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... PubChem is a database of chemical molecules. ... The DrugBank database available at the University of Alberta is a unique bioinformatics and cheminformatics resource that combines detailed drug (i. ... This article or section does not cite any references or sources. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Standard atomic weight 12. ... General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless gas Standard atomic weight 14. ... General Name, Symbol, Number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Standard atomic weight 15. ... The molecular mass (abbreviated Mr) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... In pharmacology, bioavailability is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ... Drug metabolism is the metabolism of drugs, their biochemical modification or degradation, usually through specialized enzymatic systems. ... It has been suggested that Effective half-life be merged into this article or section. ... Excretion is the process of eliminating waste products of metabolism and other materials that are of no use. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...

Legal status

? The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ...

Routes Oral

Mebendazole (brand name Ovex®, Vermox®, Antiox® or Pripsen®) is a drug commonly used to combat pinworms, roundworms and hookworms. It is sometimes referred to as "MBZ". Mebendazole (C16H13N3O3) causes slow immobilization and death of the worms by selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where helminths dwell. It is a spindle poison that induces chromosome nondisjunction. Oral dosage is 100 mg 12 hourly for 3 days, although sometimes the dosage is just one 500 mg dose, followed by another dose two weeks later if the infection has not cleared up. The dosage may differ depending on which type of worm someone is infected with. In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... The pinworm (Genus Enterobius) is a parasitic roundworm of the phylum Nematoda. ... Classes Adenophorea    Subclass Enoplia    Subclass Chromadoria Secernentea    Subclass Rhabditia    Subclass Spiruria    Subclass Diplogasteria The roundworms or nematodes (Phylum Nematoda from Gr. ... Species Species N. americanus and A. duodenale The hookworm is a parasitic worm (nematode) that lives in the small intestine of its host, which may be a mammal such as a dog, cat, or human. ... These poisons disrupt cellular reproduction by affecting the protein threads which connect the centromere regions of chromosomes, known as spindles. ... Figure 1: A representation of a condensed eukaryotic chromosome, as seen during cell division. ... Nondisjunction is the failure of the chromosomes to properly segregate during meiotic or mitotic anaphase, resulting in daughter cells with abnormal numbers of chromosomes. ... The milligram (symbol mg) is an SI unit of mass. ...


See also

Johnson & Johnson NYSE: JNJ is an international pharmaceutical, medical devices and consumer packaged goods manufacturer founded in 1885. ...

External links

  • Vermox (UK manufacturer's website)

  Results from FactBites:
 
mebendazole - [Medication] (1036 words)
Mebendazole is used to treat infections caused by worms such as whipworm, pinworm, roundworm, and hookworm.
Mebendazole is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby.
Mebendazole is available with a prescription under the brand name Vermox in 100 mg chewable tablets.
  More results at FactBites »


 

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