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Encyclopedia > Memory B cell

Memory B cells are a B cell sub-type that are formed following primary infection. When a B cell is activated, by recognizing a specific antigen, it proliferates to form antibody producing plasma cells and long-lived memory cells. The memory B cells are specific for the antigen that first stimulated their production. If this antigen is encountered again, memory B cells can recognize it and quickly proliferate. This forms a new generation of antibody-producing plasma cells. This means that the antibody response is much more rapid in subsequent infections, than in primary infection, reducing the chance of symptom development. This is the principle behind vaccination. B cells are lymphocytes that play a large role in the humoral immune response (as opposed to the cell-mediated immune response). ... An antigen is a molecule that stimulates the production of antibodies. ... Plasma cells are B lymphocytes that secrete immunoglobulins (antibodies). ... Vaccination is a term coined by Edward Jenner for the process of administering live, albeit weakened, microbes to patients, with the intent of conferring immunity against a targeted form of a related disease agent. ...



Blood - Blood plasma
Pluripotential hemopoietic stem cell - Red blood cells (Reticulocyte, Normoblast) - White blood cells
Lymphocytes (Lymphoblast)
T cells (Cytotoxic - Helper - Regulatory T cell) - B cells (Plasma cells & Memory B cells) - Natural killer cell
Myelocytes (Myeloblast)
Granulocytes (Neutrophil, Eosinophil, Basophil) - Mast cell precursors - Monocytes (Histiocyte, Macrophages, Dendritic cells, Langerhans cells, Microglia, Kupffer cells) - Megakaryoblast - Megakaryocyte - Platelets


Red blood cells (erythrocytes) are present in the blood and help carry oxygen to the rest of the cells in the body Blood is a circulating tissue composed of fluid plasma and cells (red blood cells, white blood cells, platelets). ... Blood plasma is the liquid component of blood, in which the blood cells are suspended. ... Sketch of bone marrow and its cells Pluripotential hemopoietic stem cells or pluripotential hematopoietic stem cells (PHSCs) are stem cells found in the bone marrow. ... Human red blood cells Red blood cells are the most common type of blood cell and are the vertebrate bodys principal means of delivering oxygen from the lungs or gills to body tissues via the blood. ... Reticulocytes are immature red blood cells, that normally comprise about 1% of the red cells in the human body. ... A normoblast (or erythroblast) is a type of red blood cell which still retains a cell nucleus. ... White blood cells (also called leukocytes or immune cells) are a component of blood. ... This article has been identified as possibly containing errors. ... Lymphoblasts are interferons produced predominantly by leucocyte cells. ... T cells are a subset of lymphocytes that play a large role in the immune response. ... A cytotoxic (or TC) T cell is a T cell (a type of white blood cell) which has on its surface antigen receptors that can bind to fragments of antigens displayed by the Class I MHC molecules of virus (or other intracellular pathogen) infected somatic cells and tumor cells. ... A T helper cell (or TH cell), is a T cell (a type of white blood cell or leukocyte) that only plays a role in the adaptive immune system. ... Regulatory T cells (also known as suppressor T cells) are a specialized subpopulation of T cells that act to suppress activation of the immune system and thereby maintain immune system homeostasis and tolerance to self. ... B cells are lymphocytes that play a large role in the humoral immune response (as opposed to the cell-mediated immune response). ... Plasma cells (also called plasma B cells) are cells of the immune system that secrete large amounts of antibodies. ... Natural killer cells (also known as NK cells, K cells, and killer cells) are a type of lymphocyte (a white blood cell) and a component of innate immune defense. ... Sketch of bone marrow and its cells Pluripotential hemopoietic stem cells or pluripotential hematopoietic stem cells (PHSCs) are stem cells found in the bone marrow. ... Myeloblasts or blasts are new, immature blood cells developed in the bone marrow that are the precursors of myelocytes. ... Granulocytes are a category of white blood cells, characterised by the fact that all types have differently staining granules in their cytoplasm on light microscopy. ... Neutrophil granulocytes, generally referred to as neutrophils, are a class of white blood cells and are part of the immune system. ... Eosinophils are white blood cells that are responsible for combating infection by parasites in the body. ... This article needs to be cleaned up to conform to a higher standard of quality. ... A mast cell (or mastocyte) is a resident cell of connective tissue that contains many granules rich in histamine and heparin. ... A monocyte is a leukocyte, part of the human bodys immune system that protect against blood-borne pathogens and move quickly to sites of infection in the tissues. ... A Histiocyte is a cell that is part of the human immune system. ... Macrophages (Greek: big eaters) are cells found in tissues that are responsible for phagocytosis of pathogens, dead cells and cellular debris. ... Dendritic cells (DC) are immune cells and form part of the mammal immune system. ... Langerhans cells are immature dendritic cells containing large granules called Birbeck granules. ... Microglia act as the immune cells of the Central nervous system (CNS). ... Kupffer cells are reticulendothelial cells located in the liver. ... A megakaryoblast is a precursor cell to a promegakaryocyte, which in turn becomes a megakaryocyte. ... The megakaryocyte is a bone marrow cell responsible for the production of blood platelets when cytoplasm processes become fragmented. ... A 250 ml bag of newly collected platelets. ...

Immune system
Humoral immune system - Cellular immune system - Lymphatic system - White blood cells - Antibodies - Antigen (MHC)

  Results from FactBites:
 
immuteach - milestones - b cell memory (140 words)
There is evidence that B cell memory, which is mediated by antibodies, can be effective for many years.
This memory is carried by memory B cells that recognize antigen by high-affinity antibodies.
A lot of research was focussed on the mechanism of the long-term survival of memory B cells.
Immune memory from smallpox vaccination lasts more 50 years, according to Emory research (841 words)
Vaccinia virus-specific B cells were detected in most of the previously vaccinated individuals in the study, including those vaccinated up to 60 years after vaccination.
Memory B cells are responsible for stimulating a rapid antibody response after re-exposure to infection.
In order to test the functionality of the memory B cells, the scientists revaccinated a group of test subjects who had been vaccinated between 22 and 48 years earlier, and detected 20-fold increases in vaccinia-virus antibodies after the second vaccination.
  More results at FactBites »


 

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