The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. It is available as a book titled Mendelian Inheritance in Man (MIM), which is currently in its 12th edition. A database is a collection of information stored in a computer in a systematic way, such that a computer program can consult it to answer questions. ... A disease is any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. ... A genetic disorder, or genetic disease is a disease caused, at least in part, by the genes of the person with the disease. ... This stylistic schematic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). ... Human genome is the genome of Homo sapiens. ... Mendelian inheritance (or Mendelian genetics or Mendelism) is a set of primary tenets that underlie much of genetics developed by Gregor Mendel in the latter part of the 19th century. ...

The online version is called Online Mendelian Inheritance in Man, which can be accessed with the Entrez database searcher of the National Library of Medicine. Online means being connected to the Internet or another similar electronic network, like a bulletin board system. ... The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ... The U.S. National Library of Medicine (NLM), operated by the U.S. federal government, is the worlds largest medical research library. ...

OMIM™ and Online Mendelian Inheritance in Man™ are trademarks of the Johns Hopkins University. The Johns Hopkins University is an internationally prestigious private institution of higher learning located in Baltimore, Maryland. ...

Collection process

The information in this database is collected and processed under the leadership of Dr. Victor A. McKusick at Johns Hopkins University, assisted by and a team of science writers and editors. Relevant articles are identified, discussed and written up in the relevant entries in the MIM database A database is a collection of information stored in a computer in a systematic way, such that a computer program can consult it to answer questions. ... Victor Almon McKusick (born October 21, 1921) is a professor of genetics at Johns Hopkins University and main instigator of Mendelian Inheritance in Man, now often referred to unofficially as the McKusick catalogue. Biography He was born on a dairy farm in Parkman, Maine; an identical twin, Vincent would qualify... The Johns Hopkins University is an internationally prestigious private institution of higher learning located in Baltimore, Maryland. ... What is science? There are different theories of what science is. ...

The MIM code

Every disease and gene is assigned a six digit number of which the first number classifies the method of inheritance. This stylistic schematic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). ...

An autosome is a non-sex chromosome. ... The word locus (plural loci) is Latin for place. In biology, a locus is the position of a gene (or other significant sequence) on a chromosome. ... The phenotype of an individual organism is either its total physical appearance and constitution, or a specific manifestation of a trait, such as size or eye color, that varies between individuals. ... An autosome is a non-sex chromosome. ... The word locus (plural loci) is Latin for place. In biology, a locus is the position of a gene (or other significant sequence) on a chromosome. ... The phenotype of an individual organism is either its total physical appearance and constitution, or a specific manifestation of a trait, such as size or eye color, that varies between individuals. ... Sex-linked genes are those carried on the mammalian X chromosome but not the Y chromosome. ... The word locus (plural loci) is Latin for place. In biology, a locus is the position of a gene (or other significant sequence) on a chromosome. ... The phenotype of an individual organism is either its total physical appearance and constitution, or a specific manifestation of a trait, such as size or eye color, that varies between individuals. ... The word locus (plural loci) is Latin for place. In biology, a locus is the position of a gene (or other significant sequence) on a chromosome. ... The phenotype of an individual organism is either its total physical appearance and constitution, or a specific manifestation of a trait, such as size or eye color, that varies between individuals. ... In cell biology, a mitochondrion is an organelle found in the cells of most eukaryotes. ... The word locus (plural loci) is Latin for place. In biology, a locus is the position of a gene (or other significant sequence) on a chromosome. ... The phenotype of an individual organism is either its total physical appearance and constitution, or a specific manifestation of a trait, such as size or eye color, that varies between individuals. ... An autosome is a non-sex chromosome. ... The word locus (plural loci) is Latin for place. In biology, a locus is the position of a gene (or other significant sequence) on a chromosome. ... The phenotype of an individual organism is either its total physical appearance and constitution, or a specific manifestation of a trait, such as size or eye color, that varies between individuals. ...

References

• Table from the OMIM FAQ (http://www.ncbi.nlm.nih.gov/Omim/omimfaq.html)
• McKusick VA. Mendelian Inheritance in Man; A Catalog of Human Genes and Genetic Disorders. Baltimore, MD: The Johns Hopkins University Press, 1998. ISBN 0-8018-5742-2.

External link

• Online Mendelian Inheritance in Man (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM) (to search OMIM)