Metalloproteinases (or metalloproteases) constitute a family of enzymes from the group of proteinases.
Metalloproteinases bind a metal ion such as Zn2+ or Ca2+ in their active site.
Important metalloproteinases are the bacterial enzyme thermolysin (which is a metalloendopeptidase), the digestive enzymes carboxypeptidase A or B (which are metallocarboxypeptidases), and the matrix metalloproteinases (MMP, also metalloendopeptidases).
Increased Expression of Membrane-Type Matrix Metalloproteinase and Preferential Localization of Matrix Metalloproteinase-2 to the Neointima of Balloon-Injured Rat Carotid Arteries -- Jenkins et al.
Matrix metalloproteinases of vascular wall cells are increased in balloon-injured rat carotid artery.
Metalloproteinase Inhibition and the Response to Angioplasty and Stenting in Atherosclerotic Primates
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