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A Molecular Classification for Precancerous Lesions - Cancer Biomarkers Research Group (1852 words) |
 | Molecular changes occurring early in the neoplastic process are more likely to be the most fundamental alterations occurring in cancer. |
| Although specimens are often difficult to obtain for study, technically it may be easier to develop a molecular classification of precancerous lesions, since there may be less cellular heterogeneity, fewer genetic abnormalities, and theoretically less intraneoplastic and interneoplastic diversity than with invasive cancers. |
| Following the work of the experts, examples of the precancerous lesions along with the terminology should be annotated in detail on the Interent with images and clinical and pathological features as a reference so that pathologists, molecular biologists, and others can become familiar with the specific terminology and histology. |
| Lesion definition - Medical Dictionary definitions of popular medical terms (476 words) |
| A benign lesion is non-cancerous whereas a malignant lesion is cancerous. |
| For instance, a Ghon lesion (or Ghon focus) is the scar-like "signature" in the lungs of adults left by tuberculosis in childhood. |
| The basis of sickle cell disease is a molecular lesion, one that is not even visible with a microscope but is only detectable on the molecular (protein or DNA) level. |
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