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Encyclopedia > Myopathy
Myopathy
Classification & external resources
ICD-10 G71. - G72.
ICD-9 359.4 - 359.9
DiseasesDB 8723
eMedicine emerg/328 
MeSH D009135

In medicine, a myopathy is a neuromuscular disease in which the muscle fibers do not function for any one of many reasons, resulting in muscular weakness. "Myopathy" simply means muscle disease (myo- Greek μυσ "muscle" + -pathy Greek "suffering"). This meaning implies that the primary defect is within the muscle, as opposed to the nerves ("neuropathies" or "neurogenic" disorders) or elsewhere (e.g., the brain etc.). Muscle cramps, stiffness, and spasm can also be associated with myopathy. The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or diseases, as classified by the World Health Organization (WHO). ... // G00-G99 - Diseases of the nervous system (G00-G09) Inflammatory diseases of the central nervous system (G00) Bacterial meningitis, not elsewhere classified (G01) Meningitis in bacterial diseases classified elsewhere (G02) Meningitis in other infectious and parasitic diseases classified elsewhere (G03) Meningitis due to other and unspecified causes (G04) Encephalitis, myelitis... // G00-G99 - Diseases of the nervous system (G00-G09) Inflammatory diseases of the central nervous system (G00) Bacterial meningitis, not elsewhere classified (G01) Meningitis in bacterial diseases classified elsewhere (G02) Meningitis in other infectious and parasitic diseases classified elsewhere (G03) Meningitis due to other and unspecified causes (G04) Encephalitis, myelitis... The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The Disease Bold textDatabase is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ... eMedicine is an online clinical medical knowledge base that was founded in 1996. ... Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... medicines, see Medication. ... The term disease refers to an abnormal condition of an organism that impairs function. ... Global view of a neuromuscular junction: 1. ... Muscle weakness (or lack of strength) is the inability to exert force with ones muscles to the degree that would be expected given the individuals general physical fitness. ... Neuropathy strictly speaking is any disease that affects the neurons of the nervous system. ... The nervous system of an animal coordinates the activity of the muscles, monitors the organs, constructs and processes input from the senses, and initiates actions. ... This article is about muscular pain. ... Stiffness is the resistance of an elastic body to deflection or deformation by an applied force. ... A spasm is a sudden, involuntary contraction of a muscle, a group of muscles, or a hollow organ, or a similarly sudden contraction of an orifice. ...


Classes

Because myopathy is such a general term, there are several classes of myopathy.... (ICD-10 codes are provided where available.) The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ...

  • (G71.0) Dystrophies (or muscular dystrophies) are a subgroup of myopathies characterized by muscle degeneration and regeneration. Clinically, muscular dystrophies are typically progressive, because the muscles' ability to regenerate is eventually lost, leading to progressive weakness, often leading to use of a wheelchair, and eventually death, usually related to respiratory weakness.
  • (G71.1) Myotonia
  • (G71.2) The congenital myopathies do not show evidence for either a progressive dystrophic process (i.e., muscle death) or inflammation, but instead characteristic microscopic changes are seen in association with reduced contractile ability of the muscles. Among others, different congenital myopathies include:
  • (G71.3) Mitochondrial myopathies are due to defects in mitochondria, which provide a critical source of energy for muscle.
  • (G72.3) Familial periodic paralysis
  • (G72.4) Inflammatory myopathies are caused by problems with the immune system attacking components of the muscle, leading to signs of inflammation in the muscle.
  • (G73.6) Metabolic myopathies result from defects in biochemical metabolism that primarily affect muscle
  • (M33.0-M33.1) Dermatomyositis, (M33.2) polymyositis, inclusion body myositis, and related myopathies
  • (M61) Myositis ossificans
  • (M62.89) Rhabdomyolysis and (R82.1) myoglobinurias
  • Common muscle (R25.2) cramps and (M25.6) stiffness, and (R29.0) tetany

Muscular dystrophy refers to a group of genetic, hereditary muscle diseases that cause progressive muscle weakness. ... This article does not cite any references or sources. ... Myotonia is a neuromuscular disorder characterized by the slow relaxation of the muscles after voluntary contraction or electrical stimulation. ... Neuromyotonia is spontaneous muscular activity resulting from repetitive motor unit action potentials of peripheral origin. ... Congenital myopathy is a term for any muscle disorder present at birth. ... Nemaline myopathy (NM; also called rod myopathy or nemaline rod myopathy) is a group of congenital, hereditary neuromuscular disorders that cause muscle weakness, generally nonprogressive, of varying severity. ... Note: Centronuclear myopathy includes Myotubular myopathy, as outlined below. ... Note: Centronuclear myopathy includes Myotubular myopathy, as outlined below. ... HeLa cells stained for DNA with the Blue Hoechst dye. ... In medical circles, wasting refers to the process by which a debilitating disease causes muscle and fat tissue to waste away. ... A congenital disorder is a medical condition or defect that is present at or before birth (for example, congenital heart disease). ... Sex-linked genes are those carried on the mammalian X chromosome but not the Y chromosome. ... Note: Centronuclear myopathy includes Myotubular myopathy, as outlined below. ... Note: Centronuclear myopathy includes Myotubular myopathy, as outlined below. ... Note: Centronuclear myopathy includes Myotubular myopathy, as outlined below. ... In genetics, the term recessive gene refers to an allele that causes a phenotype (visible or detectable characteristic) that is only seen in a homozygous genotype (an organism that has two copies of the same allele). ... Note: Centronuclear myopathy includes Myotubular myopathy, as outlined below. ... It has been suggested that this article or section be merged into Dominance relationship. ... Mitochondrial myopathy are a type of myopathy associated with mitochondrial disease. ... In cell biology, a mitochondrion is an organelle found in the cells of most eukaryotes. ... Familial periodic paralysis is a form of myopathy that are inherited. ... An abscess on the skin, showing the redness and swelling characteristic of inflammation. ... Glycogen storage disease is any one of several inborn errors of metabolism that result from enzyme defects that affect the processing of glycogen synthesis or breakdown within muscles, liver, and other cell types. ... Lipid storage disorders (or lipidoses) are a group of inherited metabolic disorders in which harmful amounts lipids (fats) accumulate in some of the body’s cells and tissues. ... X-Ray of the knee in a patient with dermatomyositis. ... {{ }} Polymyositis is a type of inflammatory myopathy, related to dermatomyositis and inclusion body myositis. ... Inclusion body myositis (IBM) is an inflammatory muscle disease, characterized by slowly progressive wasting and weakness of the arms and legs. ... Myositis ossificans comprises two syndromes characterized by heterotopic calcification of muscle. ... Rhabdomyolysis is the breakdown of skeletal muscle due to injury, either mechanical, physical or chemical. ... Myoglobinuria is the presence of myoglobin in the urine, usually associated to rhabdomyolysis or muscle destruction. ... A cramp is an unpleasant sensation caused by contraction, usually of a muscle. ... Stiffness is the resistance of an elastic body to deflection or deformation by an applied force. ... Diseases and other conditions that increase action potential frequency cause unwanted contraction of muscles. ...

Treatments

Because different types of myopathies are caused by many different pathways, there is no single treatment for myopathy. Treatments range from treatment of the symptoms to very specific cause-targeting treatments. Drug therapy, physical therapy, bracing for support, surgery, and even acupuncture are current treatments for a variety of myopathies. This article is being considered for deletion in accordance with Wikipedias deletion policy. ... Physical therapy (or physiotherapy[1]) is the provision of services to people and populations to develop, maintain and restore maximum movement and functional ability throughout the lifespan. ... “Surgeon” redirects here. ... Acupuncture chart from Hua Shou (fl. ...


  Results from FactBites:
 
Myopathy - Wikipedia, the free encyclopedia (478 words)
In medicine, a myopathy is a neuromuscular disease in which the muscle fibers dysfunction for any one of many reasons, resulting in muscular weakness.
A less severe form of centronuclear myopathy that may present itself at birth or in early childhood progresses slowly and is inherited as an autosomal recessive genetic trait.
The least severe of the three forms of centronuclear myopathy first appears during the second and third decades of life and is slowly progressive; it is inherited as an autosomal dominant genetic trait.
Nemaline myopathy - Wikipedia, the free encyclopedia (846 words)
Nemaline myopathy (also called rod myopathy or nemaline rod myopathy) is a group of congenital, hereditary neuromuscular disorders that cause muscle weakness, generally nonprogressive, of varying severity.
"Myopathy" means "muscle disease," and a biopsy of muscle from a person with nemaline myopathy shows abnormal thread-like rods, called nemaline bodies, in the muscle cells.
Genetic mutations found to be responsible for the disorder include the alpha-actin gene, the nebulin gene, tropomyosin 2 gene, tropomyosin 3 gene, and troponin T. The physical capabilities of a given person with NM do not correlate well either with genotype or with muscle pathology as observed in the biopsy.
  More results at FactBites »


 

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