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NSAIDs are used primarily to treat inflammation, mild to moderate pain, and fever.
NSAIDs vary in their potency, duration of action, and the way in which they are eliminated from the body.
NSAIDs reduce blood flow to the kidneys and therefore reduce the action of diuretics and decrease the elimination of lithium (Eskalith) and methotrexate (Rheumatrex).
NSAIDs (pronounced "en-seds") are probably the most widely used class of drugs in the country.
As their name implies, NSAIDs work by checking inflammation, which is the immune system's way of responding to injury.
In short, that means that although NSAIDs can ease joint pain (for example), they also may cause damage to the mucosa in healthy people or reactivate the symptoms of disease in IBD patients.