Encyclopedia > National Center for Biotechnology Information
 National Center for Biotechnology Information logo The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health. The NCBI is located in Bethesda, Maryland and was founded in 1988. The NCBI houses genome sequencing data in GenBank and an index of biomedical research articles in PubMed Central and PubMed, as well as other information relevant to biotechnology. All these databases are available online through the Entrez search engine. Image File history File links No higher resolution available. ...
The United States National Library of Medicine (NLM), operated by the United States federal government, is the worlds largest medical library. ...
National Institutes of Health Building 50 at NIH Clinical Center - Building 10 The National Institutes of Health (NIH) is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical research. ...
Bethesda is an urbanized, but unincorporated, area in southern Montgomery County, Maryland, near Washington, D.C. It takes its name from a church located there, the Bethesda Presbyterian Church, built in 1820 and rebuilt in 1850, which in turn took its name from Jerusalems Pool of Bethesda. ...
Year 1988 (MCMLXXXVIII) was a leap year starting on Friday (link displays 1988 Gregorian calendar). ...
In biology the genome of an organism is the whole hereditary information of an organism that is encoded in the DNA (or, for some viruses, RNA). ...
In genetics and biochemistry, sequencing means to determine the primary structure (or primary sequence) of an unbranched biopolymer. ...
The GenBank sequence database is an annotated collection of all publicly available nucleotide sequences and their protein translations. ...
PubMed Central grew from the online Entrez PubMed biomedical literature search system. ...
Medline is a comprehensive literature database of life sciences and biomedical information. ...
The structure of insulin Biological technology is technology based on biology, especially when used in agriculture, food science, and medicine. ...
The Entrez logo The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ...
The NCBI is directed by David Lipman, one of the original authors of the BLAST sequence alignment program and a widely respected figure in Bioinformatics. He also leads an intramural research program, including groups led by Stephen Altschul (another BLAST co-author), David Landsman, and Eugene Koonin (a prolific author on comparative genomics). David J. Lipman is an American biologist who since 1989 has been the Director of NCBI (the National Center for Biotechnology Information) at the National Institutes of Health. ...
In bioinformatics, Basic Local Alignment Search Tool, or BLAST, is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of different proteins or the nucleotides of DNA sequences. ...
Map of the human X chromosome (from the NCBI website). ...
Stephen Altschul is an American mathematician who has designed algorithms that are widely used in the field of Bioinformatics. ...
In bioinformatics, Basic Local Alignment Search Tool, or BLAST, is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of different proteins or the nucleotides of DNA sequences. ...
Eugene V. Koonin (PhD) is an expert in the field of biotechnology. ...
Comparative genomics is the study of relationships between the genomes of different species or strains. ...
GenBank -
The NCBI has had responsibility for making available the GenBank DNA sequence database since 1992. GenBank coordinates with individual laboratories and other sequence databases such as those of the European Molecular Biology Laboratory (EMBL) and the DNA Database of Japan (DDBJ). The GenBank sequence database is an annotated collection of all publicly available nucleotide sequences and their protein translations. ...
The structure of part of a DNA double helix Deoxyribonucleic acid, or DNA, is a nucleic acid molecule that contains the genetic instructions used in the development and functioning of all known living organisms. ...
As of 2004, there are around 500 public and commercial biological databases. ...
The European Molecular Biology Laboratory (EMBL) is a molecular biology research institution supported by 19 countries comprising nearly all of western Europe and Israel. ...
Since 1992, NCBI has grown to provide other databases in addition to GenBank. NCBI provides Online Mendelian Inheritance in Man, the Molecular Modeling Database (3D protein structures), the Unique Human Gene Sequence Collection, a Gene Map of the Human genome, a Taxonomy Browser, and coordinates with the National Cancer Institute to provide the Cancer Genome Anatomy Project. The NCBI assigns a unique identifier (Taxonomy ID number) to each species of organism. Year 1992 (MCMXCII) was a leap year starting on Wednesday (link will display full 1992 Gregorian calendar). ...
The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ...
A graphical representation of the normal human karyotype. ...
The NCBI has software tools that are available by WWW browsing or by FTP. For example, BLAST is a sequence similarity searching program. BLAST can do sequence comparisons against the GenBank DNA database in less than 15 seconds. WWWs historical logo designed by Robert Cailliau The World Wide Web is a system of interlinked, hypertext documents accessed via the Internet. ...
In bioinformatics, Basic Local Alignment Search Tool, or BLAST, is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of different proteins or the nucleotides of DNA sequences. ...
NCBI Bookshelf The NCBI Bookshelf is a collection of freely available, on-line versions of selected biomedical books. As of March 2006, the Bookshelf had 55 titles covering aspects of molecular biology, biochemistry, cell biology, genetics, microbiology, a couple of disease states from a molecular and cellular point of view, research methods, and virology. Some of the books are online versions of previously published books, while others, such as Coffee Break, are written and edited by NCBI staff. The Bookshelf is a complement to the Entrez PubMed repository of peer-reviewed publication abstracts in that Bookshelf contents provide established perspectives on evolving areas of study and a context in which many disparate individual pieces of reported research can be organized. Molecular biology is the study of biology at a molecular level. ...
Biochemistry is the study of the chemical processes and transformations in living organisms. ...
This article or section includes a list of works cited or a list of external links, but its sources remain unclear because it lacks in-text citations. ...
DNA, the molecular basis for inheritance. ...
This article does not cite any references or sources. ...
Virology, often considered a part of microbiology or of pathology, is the study of organic viruses: their structure and classification, their ways to infect and exploit cells to reproduce and cause disease, the techniques to isolate and culture them, and their potential uses in research and therapy. ...
A coffee break is a daily social gathering for a snack and short downtime practiced by employees in business and industry. ...
Medline is a comprehensive literature database of life sciences and biomedical information. ...
Peer review (known as refereeing in some academic fields) is a scholarly process used in the publication of manuscripts and in the awarding of funding for research. ...
See also National Institutes of Health Building 50 at NIH Clinical Center - Building 10 The National Institutes of Health (NIH) is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical research. ...
The United States National Library of Medicine (NLM), operated by the United States federal government, is the worlds largest medical library. ...
It has been suggested that GoPubMed be merged into this article or section. ...
The Entrez logo The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ...
Medline is a comprehensive literature database of life sciences and biomedical information. ...
The GenBank sequence database is an annotated collection of all publicly available nucleotide sequences and their protein translations. ...
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