The National Institute for Health and Clinical Excellence or NICE is an agency of the National Health Service in the United Kingdom. It was set up as the "National Institute for Clinical Excellence" in 1999, and on 1 April 2005 joined with the Health Development Agency to become the new "National Institute for Health and Clinical Excellence" (still abbreviated as NICE). The logo of the NHS for England. ... 1999 (MCMXCIX) was a common year starting on Friday, and was designated the International Year of Older Persons by the United Nations. ...

NICE was established in order to defuse the so-called postcode lottery system of healthcare in England and Wales, where treatments that were available depended upon the NHS Trust area in which the patient happened to live. NICE publishes clinical appraisals of whether particular treatments should be considered worthwhile by the NHS, based primarily on criteria of cost-effectiveness. UK postal codes are known as postcodes. ... National Health Service Trusts (NHS Trusts) provide many services of the United Kingdom National Health Service in England and Wales. ...

Technology appraisals

Since January 2005 the NHS in England and Wales has been legally obliged to provide funding for medicines and treatments recommended by NICE's technology appraisal board. This is at least in part as a result of well-publicised postcode lottery scandals in which certain treatments are funded in one part of the UK but not in another. 2005 : January - February - March - April - May - June - July - August - September - October - November - December- → Deaths in January • 29 Ephraim Kishon • 25 Philip Johnson • 23 Johnny Carson • 22 Parveen Babi • 20 Jan Nowak-Jeziorański • 17 Virginia Mayo • 17 Zhao Ziyang • 15 Ruth Warrick • 14 Rudolph Moshammer Recent deaths Ongoing events • Tsunami relief... The National Health Service (NHS) is the publicly-funded healthcare system of the United Kingdom. ... Royal motto (French): Dieu et mon droit (Translated: God and my right) Englands location within the British Isles Languages English (de facto) Capital London de facto Largest city London Area – Total Ranked 1st UK 130,395 km² Population – Total (mid-2004) – Total (2001 Census) – Density Ranked 1st UK 50. ... For an explanation of often confusing terms such as Great Britain, Britain, United Kingdom and England, see British Isles (terminology). ... UK postal codes are known as postcodes. ...

If a technology is to be appraised by NICE then it must be reffered to them by the Secretary of State for Health. Once this has been done NICE works with the Department of Health to draw up the scope of the appraisal. Minister of Health redirects here. ... Many governments, both national and more local, have a Department of Health. This article is about the British one. ...

NICE then invite Consultee and Commentator organisations to take part in the appraisal. A Consultee organisation would include patient groups, organisations representing health care professionals and the manufacturers of the product undergoing appraisal. Consultees submit evidence during the appraisal and comment on the appraisal documents. Commentator organisations include the manufacturers of products to which the product undergoing appraisal is being compared too. They comment on the documents that have been submitted and drawn up but do not actually submit information themselves.

An independent academic centre then draws together and analyses all of the published information on the technology under appraisal and prepares and assessment report. This can be commented on by the Consultees and Commentators. Comments are then taken into account and changes made to the assessment report to produce an evaluation report. An independent Appraisal Committee then looks at the evaluation report, hears spoken testimony from clinical experts, patient groups and carers. They take their testimony into account and draw up a document known as the appraisal consultation document. This is sent to all consultees and commentators who are then able to make further comments. Once these comments have been taken into account the final document is drawn up called the final appraisal determination. This is submitted to NICE for approval.

Clinical Guidelines

NICE carries out assesments of the most appropriate treatment regimes for different diseases. This must take into account both desired medical outcomes (i.e. the best possible result for the patient) and also economic arguments regarding differing treatments.

NICE have set up several National Collaborating Centres who draw up the boundaries of the guideline, i.e. what it will cover. The National Collaborating Centre then appoints a Guideline Development Group whose job it is to work on the development of the clinical guideline. This group will consist of medical professionals, representatives of patient and carer groups and technical experts. They work together to asses the evidence for the guideline topic (e.g. clinical trials of competing products) before preparing a draft guideline.

There are then two consulation periods in which stakeholder organisations are able to comment on the draft guideline. After the second consultation period an independent Guideline Review Panel reviews the guideline and stakeholder comments and ensures that these comments have been taken into account.

The Guideline Development Group then finalises the recommendations and the National Collaboration Centre produces the final guideline. This is submitted to NICE who then formally approve the guideline and issues this guidance to the NHS. The National Health Service (NHS) is the publicly-funded healthcare system of the United Kingdom. ...

External link

• National Institute for Health and Clinical Excellence