Nephritis is inflammation of the kidney. The word comes from the Greek nephro- meaning "of the kidney" and -itis meaning "inflammation". Nephritis is often caused by infections, toxins, and auto-immune diseases. An abscess on the skin, showing the redness and swelling characteristic of inflammation. ... The kidneys are organs that filter wastes (such as urea) from the blood and excrete them, along with water, as urine. ... Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. ...
Subtypes
glomerulonephritis is inflammation of the glomeruli. (Often when the term "nephritis" is used without qualification, this is the condition meant.)
Glomerulonephritis is a primary or secondary autoimmune renal disease featuring inflammation of the glomeruli. ... Glomerulus refers to two unrelated structures in the body, both named for their globular form. ... Interstitial nephritis (or Tubulo-interstitial nephritis) is a form of nephritis affecting the interstititum of the kidneys surrounding the tubules. ... Interstitial nephritis (or Tubulo-interstitial nephritis) is a form of nephritis affecting the interstititum of the kidneys surrounding the tubules. ... Nephron of the kidney A nephron is the basic structural and functional unit of the kidney. ... Pyelonephritis is an ascending urinary tract infection that has reached the pyelum (pelvis) of the kidney (nephros in Greek). ... A urinary tract infection (UTI) is a bacterial infection that affects any part of the urinary tract. ... Lupus nephritis is an inflammation of the kidney caused by systemic lupus erythematosus (SLE), a disease of the immune system. ... A scanning electron microscope image of a single neutrophil (yellow), engulfing anthrax bacteria (orange). ...
Veterinary
Baby animals fed on powdered milk which is too rich may have intestinal troubles leading to nephritis, and possibly death. Photo of powdered milk Powdered milk is a powder made from dried milk solids. ...
Acute nephritis is most commonly caused by hypersensitivity (allergy) to drug therapy.
Chronic nephritis can similarly be due to a very large number of causes, including drug hypersensitivity, autoimmunity, infections, radiation of the kidney, obstruction of the urinary tract, hypertension (high blood pressure is a very well known cause of chronic nephritis), sickle cell disease, and polycystic disease of the kidney.
Nephritis also results from metabolic and toxic disorders, including the deposition of urates (uric acid) in the kidney, hypercalcemia (high blood calcium) with deposition of calcium in the kidney, chronic lead intoxication, and cadmium toxicity.
In the treatment of patients with pediatric lupus nephritis, early therapy to control the disease should be balanced with long-term follow-up to minimize the adverse effects of therapy and the disease complications.
Pregnant patients with lupus nephritis are prone to preeclampsia.
Mesangial proliferative lupus nephritis with moderate mesangial hypercellularity.