OSA is an acronym which can stand for: Acronyms and initialisms are abbreviations formed from the initial letter or letters of words, such as NATO and XHTML, and are pronounced in a way that is distinct from the full pronunciation of what the letters stand for. ...
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OSA usually arises in the medullary cavity, penetrates the cortex, and extends into the subperiosteum, causing the formation of a large soft tissue mass contiguous to the bone.
OSA is poorly delimited radiographically because there is a wide zone of transition between abnormal and normal bone that lacks a sclerotic border at the margin of the lesion.
OSA may have a heterogeneous appearance histologically and have been classified as poorly differentiated, fibroblastic, osteoblastic, telangectatic, giant cell, or chondroblastic based upon the character of the neoplastic cell population and the type(s) of matrix produced.