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Opportunistic Infections in Immunodeficient Populations (996 words) |
 | Assessments of the prevalence and incidence of opportunistic infections in these areas and comparability of the available data are hampered by limited access to care, diagnostic capabilities, and surveillance data. |
 | The opportunistic infections in these patients originate from endogenous flora (e.g, invasive candidiasis), from the general (nonhospital) environment (e.g, histoplasmosis, TB, disseminated strongyloidiasis), or from the hospital environment (e.g, aspergillosis, legionellosis, and infections with vancomycin-resistant enterococci or multiply resistant gram-negative bacteria). |
 | For example, in bone marrow transplant recipients, infections within 1 month of transplantation (pre-engraftment) occur as a result of neutropenia and disruption of mucosal surfaces; infections that occur in the second or third months are due to deficiencies in cell-mediated immunity and are more frequent in the setting of graft versus host disease. |
| CCFA.org: opportunistic infections (1711 words) |
 | Opportunistic infections also include infections like herpes and tuberculosis, which affect people with a normal immune system, but which are more severe or occur more frequently in people with a weakened immune system. |
 | Furthermore, opportunistic infections are a frequent cause of relapse or disease flares in IBD patients. |
 | Opportunistic infections in the course of steroid therapy result primarily from prolonged exposure to high doses (greater than prednisone 20 mg/day). |