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Encyclopedia > Optic atrophy

Optic atrophy is a pathological term and somewhat misleading. The term optic neuropathy is often used instead. In medicine, atrophy usually means shrunken but capable of regrowth. Optic atrophy means that on microscopic examination most of the fibers of the optic nerve are degenerated (dead). The optic nerve is part of the brain and has no capability for regeneration. Hence, there can be no recovery from optic atrophy and the term may refer to serious or mild, but always irreversible visual loss due to damage to the optic nerve. There may be symptoms associated with loss of vision (although there may be a particular difficulty with colour vision). Optic atrophy can be congenital or acquired. The optic nerve is the nerve that transmits visual information from the retina to the brain. ... In the anatomy of animals, the brain, or encephalon, is the supervisory center of the nervous system. ... The optic nerve is the nerve that transmits visual information from the retina to the brain. ... Visual perception is one of the senses, consisting of the ability to detect light and interpret (see) it as the perception known as sight or naked eye vision. ...


If congenital, it is usually hereditary with an onset of deterioration in childhood and may be accompanied by nystagmus. Leber's Hereditary Optic Neuropathy, (LHON) or Leber Optic Atrophy is hereditary, but typically has its onset in 20-30 year old males. This is due to a mutation of the mitochondrial genome and hence is passed exclusively through the mothers. Alternatively, congenital optic atrophy can be caused by a lack of oxygen during pregnancy, labour or in the early days of a child's life. Some drugs taken during pregnancy are also associated with optic atrophy. Nystagmus is rapid involuntary rhythmic eye movement, with the eyes moving quickly in one direction (quick phase), and then slowly in the other (slow phase). ... Leber’s hereditary optic neuropathy (LHON) is a maternally inherited form of acute or subacute loss of central vision that may lead to degeneration of retinal ganglion cells (RGCs) and their axons; this affects predominantly young adult males. ...


The acquired type of optic atrophy may be due to blood supply changes in the eye or optic nerve (anterior ischemic optic neuropathy or posterior ischemic optic neuropathy), may be secondary to inflammation or swelling within the optic nerve (optic neuritis), may be a result of pressure against the optic nerve (such as from a tumour), or may be related to metabolic diseases (e.g., diabetes), trauma, glaucoma, or toxicity (caused by alcohol, tobacco, or other poisons). Anterior ischemic optic neuropathy (AION) is a medical condition including loss of vision due to damage to the optic nerve. ... This article needs to be cleaned up to conform to a higher standard of quality. ... Optic neuritis is the inflammation of the optic nerve that may cause a complete or partial loss of vision. ... Tumor (American English) or tumour (British English) originally means swelling, and is sometimes still used with that meaning. ... This article is about the disease that features high blood sugar. ... Trauma can represent: A serious and often body-altering physical injury, such as the removal of a limb. ... Toxicity (from Greek τοξικότητα - poisonousness) is a measure to the degree to which something is toxic or poisonous. ... In general usage, alcohol (from Arabic al-khwl الكحول, or al-ghawl الغول) refers almost always to ethanol, also known as grain alcohol, and often to any beverage that contains ethanol (see alcoholic beverage). ... Species N. glauca N. longiflora N. rustica N. sylvestris N. tabacum Ref: ITIS 30562 as of 2002-08-28 Tobacco () is a broad-leafed plant of the nightshade family, indigenous to North and South America, whose dried and cured leaves are often smoked (see tobacco smoking) in the form of... The skull and crossbones symbol traditionally used to label a poisonous substance. ...


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  Results from FactBites:
 
HerbChina2000.com - Herbal Remedies - Optic atrophy (1059 words)
Optic atrophy may also be referred to as optic nerve head pallor because of the pale appearance of the optic nerve head as seen at the back of the eye.
In primary optic atrophy (usually due to pathology distant from the nerve head), the disk is white or grayish with sharp edges.
In secondary optic atrophy (usually due to pathology at the nerve head), the disk is dirty-white with irregular, indistinct margins and is covered by glial tissue that conceals the lamina cribrosa.
Leber hereditary optic neuropathy -- Man et al. 39 (3): 162 -- Journal of Medical Genetics (6121 words)
Leber hereditary optic neuropathy (LHON) is a mitochondrial
Optic nerve sheath distention in Leber's optic neuropathy and the significance of the "Wallace mutation".
Leber hereditary optic neuropathy: mitochondrial mutations and degeneration of the optic nerve.
  More results at FactBites »


 

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