Optic nerve hypoplasia is a medical condition that results in underdevelopment of the optic nerves.

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	Fact Sheet Optic Nerve Hypoplasia (1277 words) TM Optic Nerve Hypoplasia (ONH) refers to the underdevelopment of the optic nerve during pregnancy. The dying back of optic nerve fibers as the child develops in utero is a natural process, and ONH may be an exaggeration of that process. Midline anomalies of the brain: septo optic dysplasia (absence of the septum pellucidum and the corpus callosum), encephaloceles, anomalies of the ventricles, anencephaly, cerebral atrophy, and rarely, tumors. ON Hypoplasia (1697 words) In optic nerve hypoplasia, the missing nerve fibers may have represented central vision in the patient and, as a consequence, the patient may have very poor central vision and be considered legally blind (equal to or worse than 20/200 visual acuity). Optic nerve hypoplasia is often associated with other brain defects including absence of the septum pellucidum (a membrane that separates the front part of the lateral ventricles of the brain), agenesis of the corpus callosum (connects the left and right sides of the brain) and dysplasia of the anterior third ventricle. ONH may also be associated with the infant having nystagmus, where the eyes constantly move back-and-forth or the infant may have "wondering" eye movements in which the patient appears to be continuously looking around but fails to respond to visual stimuli.
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