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Flux, Entropy, and Cancer by Keith Duguay (5765 words) |
 | Carcinogenesis from organochlorine exposure is usually classified as either genotoxic (prone to inducing genetic mutation) or immunotoxic (toxins mimic thyroid and/or steroid hormones) [ibid.] Some of the known organochlorine compounds are non-volatile [ibid.; Koivusalo et al., 1995]; others are volatile and their environmental concentration has been positively correlated with mutagenicity [Cheh, 1980]. |
| The bioaccumulated concentration of a stable, non-excretable compound in a cell is the result of rates of movement of a limiting component of that compound from the environment, past all the particular membranes, and into the cell. |
| This is because trihalomethane compounds are genotoxic, affecting DNA in the nucleus of the cell. |
| ORGANOCHLORINE COMPOUNDS IN A SEDIMENT CORE FROM THE CORALVILLE RESERVOIR, IOWA (2263 words) |
| Organochlorine compounds were used extensively in the Iowa River watershed as insecticides during the 1960's and early 1970's (Sato and Schnoor, 1991). |
| The purpose of this factsheet is to describe the concentrations of selected organochlorine compounds in sediment cores from the Coralville Reservoir and to relate the results to the depositional period of the sediments to indicate possible trends. |
| A secondary purpose is to compare organochlorine compound concentrations in Coralville Reservoir sediments to concentrations in the Iowa River to evaluate whether compounds found in sediments are representative of those in the water. |
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