Orthostatic intolerance is the failure of the body to properly adjust to an upright position, especially with respect to blood flow, heart rate, and blood pressure.

A common manifestation of chronic orthostatic intolerance is postural orthostatic tachycardia syndrome. In medicine, a chronic disease is a disease which has developed slowly or gradually. ... Postural orthostatic tachycardia syndrome (or POTS) is a condition of orthostatic intolerance in which a change from the supine position to an upright position causes an abnormally-high increase in heart rate. ...

Orthostatic intolerance may result from crippled norepinephrine receptors that lack the ability to receive norepinephrine. Norepinephrine is one of many chemicals that help to control the blood pressure.

The loss of orthostatic tolerance is also an undesirable consequence of human adaptation to space and has often been emulated in head-down bed rest studies. In medicine, Orthostatic refers to the state of standing. ... // Human physiological adaptation to the conditions of space is a challenge faced in the development of human spaceflight. ...

A notable sufferer is Greg Page, formerly of The Wiggles. It is due to this illness that Page chose to leave the group. Greg Page Gregory John Page (born January 16, 1972 in Sydney, New South Wales, Australia) is an Australian musician and actor. ... The Wiggles are an Australian band that specializes in childrens entertainment. ...

See also

• Orthostatic hypotension

External Links: http://www.supportdysautonomia.org Orthostatic hypotension (also known as postural hypotension and, colloquially, as head rush) is a sudden fall in blood pressure, typically greater than 20/10 mm Hg, that occurs when a person assumes a standing position. ...