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Encyclopedia > Osteomalacia
Osteomalacia
Classification & external resources
ICD-10 M83.
ICD-9 268.2
DiseasesDB 9351
eMedicine ped/2014  radio/610
MeSH D010018

Osteomalacia is a softening of the bones, resulting from defective bone mineralisation. It may show signs as pain, weakness, and fragility of the bones. Image File history File links Broom_icon. ... The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or diseases, as classified by the World Health Organization (WHO). ... // M00-M99 - Diseases of the musculoskeletal system and connective tissue (M00-M25) Arthropathies (M00-M03) Infectious arthropathies (M00) Pyogenic arthritis (M01) Direct infections of joint in infectious and parasitic diseases classified elsewhere (M02) Reactive arthropathies (M023) Reiters disease (M03) Postinfective and reactive arthropathies in diseases classified elsewhere (M05-M14... The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The Disease Bold textDatabase is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ... eMedicine is an online clinical medical knowledge base that was founded in 1996. ... Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ...

Contents

Causes

Vitamin D is a fat soluble vitamin that contributes to the maintenance of normal levels of calcium and phosphorus in the bloodstream. ... General Name, Symbol, Number calcium, Ca, 20 Chemical series alkaline earth metals Group, Period, Block 2, 4, s Appearance silvery white Standard atomic weight 40. ... Renal tubular acidosis, or RTA, is a medical condition in which the kidneys fail to dispose of a normal amount of acid into the urine, which may lead to acidosis (where the blood becomes too acidic). ... Parathyroidectomy is the surgical removal of one or more parathyroid glands. ...

Clinical features

Osteomalacia in humans starts insidiously, as aches and pains in the lumbar (lower back or spine) region and thighs, spreading later to the arms and ribs. Pain is non-radiating, symmetrical, and accompanied by tenderness in the involved bones. Proximal muscles are weak, and there is difficulty in climbing up stairs and getting up from a squatting position. Physical signs include deformities like triradiate pelvis and lordosis. The patient has a typical "waddling gait". Pathologic fractures due to weight bearing may develop. Lordosis is a term used to describe the direction of the curvature of the five lumbar and seven cervical vertebrae of the vertebral column. ...


Biochemical findings

Biochemical features are similar to rickets. Rickets is a softening of the bones in children potentially leading to fractures and deformity. ...


Radiographic characteristics

Radiological appearances include

Protrusio acetabuli is an uncommon defect of the acetabulum. ...

Treatment

Nutritional osteomalacia responds well to administration of 2000-4000 IU weekly of vitamin D for 6-12 weeks, followed by a maintenance dose of 400-600 IU daily. Dietary supplementation in the form of Soy milk or milk is recommended. Medicinal calcium in the form of calcium gluconate, lactate, or carbonate can be given. A can of Yeos soy milk, poured into a glass Soymilk (also called soya milk or soybean milk, and sometimes referred to as soy drink/beverage and even soy latte) is a beverage made from soybeans originating from China. ... A glass of cows milk. ...


See also


  Results from FactBites:
 
Osteomalacia (291 words)
Osteomalacia is a disease in which insufficient mineralization leads to a softening of the bones.
Osteomalacia can occur because of reduced exposure to sunlight (which, after touching the skin, causes the body to make vitamin D), insufficient intake of vitamin D–enriched foods (like vitamin D–fortified milk), or improper digestion and absorption of food with vitamin D (as in bowel disorders such as lactose intolerance or celiac disease).
Osteomalacia should not be confused with osteoporosis, which is a disease of normal mineralization but decreased amounts of bone.
THE MERCK MANUAL OF GERIATRICS, Ch. 49, Metabolic Bone Disease (1175 words)
Osteomalacia should be suspected in patients with typical ribbonlike cortical lucencies (pseudofractures) that are found with plain x-rays and in patients in whom the serum Ca level is low or low-normal, the serum phosphorus level is low, and the serum alkaline phosphatase and parathyroid hormone levels are high.
Osteomalacia (analogous to rickets in children) is relatively rare in the elderly, although deficiency of vitamin D and Ca is common.
Osteomalacia due to vitamin D deficiency should be suspected when the serum Ca level is low or low-normal, the serum phosphorus level is low, and the serum alkaline phosphatase and PTH levels are high.
  More results at FactBites »


 

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