P-27 are a Swissrap group from Basel, Switzerland. They came out with the very first rap track that featured rhymes in Swiss German, on the song "Murder by Dialect" (1991) featuring Black Tiger, featured on the second Fresh Stuff compilation. The first album Overdose Funk followed the same year. Lyrics were partly in English, partly in Swiss German. Their second album Jetzt funkt's aa came out in 1997, without Scen, who had left the band, but with a complete funk-band in the background. The album also and rather atypically for Swiss German rap also contains raps in Standard German. As Swiss German rap really became popular between 1997 and 1999, they dropped a third album in 2000, which was mostly unrecognized.
p27 initially earned its greatest fame among cancer biologists for its effects on cell division, which is also a key function that is disrupted in tumors.
The p27 protein was originally identified as a tumor suppressor, a type of protein that normally acts to prevent cells from dividing.
He observed that p27 interacts with a key controller of a cellÂ’s microscopic skeleton, or cytoskeleton, which is repeatedly broken down and reassembled as a cell inches along its path to a new destination.
p27 shuttles between the nucleus and cytoplasm (38, 39).
B, p27 localization in quiescent cells stimulated with TSH (T), serum (CS), or TSH/serum (T/CS) for 15 h in the same experiment as panel A. DAPI staining of the same fields is shown (left panels).
export of p27 from the nucleus temporally preceded its degradation.
Feeds |
Contact