Physical Markup Language, is an XML-based language that is used to define data on objects. Often used in conjunction with RFID tags.
Physical Model Languages, is an XML-based language designed to describe tissues and structures as physical objects using a model (discrete, continuous, ...) in order to perform a medical simulation.
Promyelocytic leukemia protein, a tumor suppressor protein forming nuclear bodies, mutated in one type of promyelocytic leukemia.
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The symptoms of PML are the result of an infection that causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain.
Typical symptoms associated with PML are diverse, since they are related to the location and amount of damage in the brain, and evolve over the course of several days to several weeks.
A positive diagnosis of PML can be made on brain biopsy, or by combining observation of a progressive course of the disease, consistent white matter lesions visible on a magnetic resonance image (MRI) scan, and the detection of the JC virus in spinal fluid.
Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells (oligodendrocytes and astrocytes) by the JC virus (JCV).
PML is an opportunistic infection associated with AIDS and certain cancers.
In PML, the JCV infects and kills the cells (oligodendrocytes) that produce myelin, which is needed to form the sheath that surrounds and protects nerves.