Panniculitis is a group of diseases whose hallmark is inflammation of subcutaneous fatty and muscle tissue. Symptoms include tender skin nodules, and systemic signs such as weight loss and fatigue. The International Statistical Classification of Diseases and Related Health Problems (commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ... The International Statistical Classification of Diseases and Related Health Problems (commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... Inflammation is the first response of the immune system to infection or irritation and may be referred to as the innate cascade. ... The panniculus adiposus is part of the subcutaneous tissue. ... A nodule describes similar aggregation of cells or particles in a number of scientific fields: In medicine it refers to a small aggregation of cells. ... Weight loss, in the context of medicine or health, is a reduction of the total body weight, which occurs when the body loses fluid, muscle mass, or fat. ... The word fatigue is used in everyday living to describe a range of afflictions, varying from a general state of lethargy to a specific work induced burning sensation within muscle. ...

Classification

Histological

It can occur in any fatty tissue (cutaneous or visceral) and is often diagnosed on the basis of a deep skin biopsy, and can be further classified by histological characteristics based on the location of the inflammatory cells (within fatty lobules or in the septa which separate them) and on the presence or absence of vasculitis. This article is about skin in the biological sense. ... A biopsy (in Greek: bios = life and opsy = look/appearance) is a medical test involving the removal of cells or tissues for examination. ... A thin section of lung tissue stained with hematoxylin and eosin. ... In medicine, vasculitis (plural: vasculitides) is a group of diseases featuring inflammation of the wall of blood vessels. ...

There are thus four main histological subtypes:

1. lobular panniculitis without vasculitis (acute panniculitis, previously termed Weber-Christian disease [1], systemic nodular panniculitis)
2. lobular panniculitis with vasculitis
3. septal panniculitis without vasculitis
4. septal panniculitis with vasculitis

Symptomatic

Panniculitis can also be classified based on the presence or absence of systemic symptoms: The term symptom (from the Greek syn = con/plus and pipto = fall, together meaning co-exist) has two similar meanings in the context of physical and mental health: A symptom can be a physical condition which shows that one has a particular illness or disorder (see e. ...

• Panniculitis without systemic disease can be a result of trauma or cold [2];
• Panniculitis with systemic disease can be caused...
  • by connective tissue disorders such as lupus erythematosus or scleroderma;
  • by lymphoproliferative disease such as lymphoma or histiocytosis;
  • by pancreatitis or pancreatic cancer;
  • and by many other causes.

In medicine, a trauma patient has suffered serious and life-threatening physical injury resulting in secondary complications such as shock, respiratory failure and death. ... Connective tissue is one of the four types of tissue in traditional classifications (the others being epithelial, muscle, and nervous tissue. ... Scleroderma is a rare, chronic disease characterized by excessive deposits of collagen. ... Lymphoproliferative disorders (LPDs) refer to several conditions in which lymphocytes are produced in excessive quantities. ... Lymphoma is a variety of cancer that originates in lymphocytes or, more rarely, of histiocytes. ... Though histiocytosis can refer to any of several specific diseases, the term is generally used to refer to a rare blood disease that is caused by an excess of white blood cells called histiocytes. ... Pancreatitis is inflammation of the pancreas. ... Pancreatic cancer (also called cancer of the pancreas) is a malignant tumour within the pancreatic gland. ...

Associated conditions

Lipoatrophy (the loss of subcutaneous tissue) can occur in any of these conditions.

See also

• Erythema induratum
• Panniculus adiposus
• Panniculus carnosis

Bazin disease (or Erythema induratum, or Nodular vasculitis) is a skin ulceration on the back of the calves. ... The panniculus adiposus is part of the subcutaneous tissue. ...

External links

• DermNetNz