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Encyclopedia > Paternity testing

A paternity test is conducted to prove paternity, that is, whether a man is the biological father of another individual. This may be relevant in view of rights and duties of the father. Similarly, a maternity test can be carried out. This is less common, because at least during childbirth and pregnancy, except in the case of a pregnancy involving embryo transfer or egg donation, it is obvious who the mother is. However, it is used in a number of events such as legal battles where a person's maternity is challenged, where the mother is uncertain because she has not seen her child for an extended period of time, or where deceased persons need to be identified. Paternity is the social and legal acknowledgment of the parental relationship between a father and his child. ... Father with child For other uses, see Father (disambiguation). ... The Fathers rights movement or Parents rights movement is part of the mens movement and/or the parents movement that emerged in the 1970s as a loose social movement providing a network of interest groups, primarily in western countries. ... Childbirth (also called labour, birth, partus or parturition) is the culmination of a human pregnancy or gestation period with the delivery of one or more newborn infants from the mothers uterus. ... This article needs additional references or sources for verification. ... Embryo transfer refers to a step in the process of in vitro fertilization (IVF) whereby one or several embryos are placed into the uterus of the female with the intent to establish a pregnancy. ... An egg donor is a woman who provides usually several eggs (ova, oocytes) for another person or couple who want to have a child. ... Faces of mother and child; detail of sculpture at Soldier Field, Chicago, Illinois, USA. Female mallard duck and ducklings. ...


Although not constituting completely reliable evidence, several congenital traits such as attached earlobes, the widow's peak, or the cleft chin, may serve as tentative indicators of (non-)parenthood as they are readily observable and inherited via autosomal-dominant genes. Several inheritable traits or congenital conditions in humans are classical examples of Mendelian inheritance: Their presence is controlled by a single gene that can either be of the autosomal-dominant or -recessive type. ... On the ear of humans and many other animals, the earlobe (lobulus auriculæ, sometimes simply lobe or lobule) is the soft lower part of the external ear or pinna. ... Widows peak A widows peak is a descending V-shaped point in the middle of the hairline (above the forehead). ... A cleft chin is unique trait resulting in a dimple on the chin. ... It has been suggested that dominant allele be merged into this article or section. ...


A more reliable way to ascertain parenthood is via DNA analysis (known as genetic fingerprinting of individuals), although older methods have included ABO blood group typing, analysis of various other proteins and enzymes, or using HLA antigens. The current techniques for paternity testing are using polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP). For the most part however, DNA has all but taken over all the other forms of testing. Genetic testing usually has a 99.999% accuracy rate, or 99,999 out of 100,000.[citation needed] Genetic fingerprinting, DNA testing, DNA typing, and DNA profiling are techniques used to distinguish between individuals of the same species using only samples of their DNA. Its invention by Sir Alec Jeffreys at the University of Leicester was announced in 1985. ... Blood type (or blood group) is determined, in part, by the ABO blood group antigens present on red blood cells. ... A representation of the 3D structure of myoglobin, showing coloured alpha helices. ... Ribbon diagram of the enzyme TIM, surrounded by the space-filling model of the protein. ... The initialism HLA can stand for: Hapag Lloyd Airlines,a German charter airline Harvey L. Atwater, a U.S. politician Henry Louis Aaron, a baseball player High Level Architecture, a distributed computer simulation standard House of Lords Act, a U.K. constitutional reform Human Leukocyte Antigen, a key part of... This article does not cite any references or sources. ... PCR tubes in a stand after a colony PCR The polymerase chain reaction (PCR) is a biochemistry and molecular biology technique[1] for exponentially amplifying DNA, via enzymatic replication, without using a living organism (such as E. coli or yeast). ... In molecular biology, the term restriction fragment length polymorphism (or RFLP, often pronounced rif-lip) is used in two related contexts: as a characteristic of DNA molecules (arising from their differing nucleotide sequences) by which they may be distinguished, as the laboratory technique which uses this characteristic to compare DNA...

Contents

DNA testing

The DNA of an individual is almost exactly the same in each and every somatic (non reproductive) cell. Sexual reproduction brings the DNA of both parents together randomly to create a unique combination of genetic material in a new cell, so the genetic material of an individual is derived from the genetic material of both their parents in roughly equal amounts. This genetic material is known as the nuclear genome of the individual, because it is found in the nucleus. The structure of part of a DNA double helix Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions for the development and function of living organisms. ... Drawing of the structure of cork as it appeared under the microscope to Robert Hooke from Micrographia which is the origin of the word cell. Cells in culture, stained for keratin (red) and DNA (green). ... Sexual reproduction is a union that results in increasing genetic diversity of the offspring. ... In biology the genome of an organism is the whole hereditary information of an organism that is encoded in the DNA (or, for some viruses, RNA). ... HeLa cells stained for DNA with the Blue Hoechst dye. ...


Comparing the DNA sequence of an individual to that of another individual can show if one of them was derived from the other or not. Specific sequences are usually looked at to see if they were copied verbatim from one of the individual's genome to the other. If that was the case, then this proves that the genetic material of one individual could have been derived from that of the other (i.e.: one is the parent of the other). Besides the nuclear DNA in the nucleus, the mitochondria in the cells also have their own genetic material termed the mitochondrial genome. Mitochondrial DNA comes only from the mother, without any shuffling. In cell biology, a mitochondrion is an organelle found in the cells of most eukaryotes. ... The mitochondrial genome is the genetic material of the mitochondria. ...


Proving a relationship based on comparison of the mitochondrial genome is much easier than that based on the nuclear genome. However, testing the mitochondrial genome can only prove if two individuals are related by common descent through maternal lines only from a common ancestor and is thus of limited value (for instance, it could not be used to test for paternity). The mitochondrial genome is the genetic material of the mitochondria. ... A group of organisms is said to have common descent if they have a common ancestor. ...


Prenatal paternity testing

Scientific tests can now determine paternity at 12 weeks into a pregnancy using non-invasive testing methods in many cases. This involves a simple blood sample taken from the pregnant woman's arm. The pregnant female's blood carries the fetus' DNA which can be compared to the DNA of the alleged father.[1] Professor Dennis Lo Yuk-ming is the Dr. Li Ka Shing Professor of Medicine and Professor of Chemical Pathology at The Chinese University of Hong Kong. He is one of the world's foremost researchers on this technology.[2]


Legal issues

In the UK, there were no restrictions on paternity tests until the Human Tissue Act came into force in September 2006. Section 45 states that it is an offence to possess without appropriate consent any human bodily material with the intent of analyzing its DNA. Legally declared fathers have access to paternity testing services under the new regulations, provided the putative parental DNA being tested is their own.


Tests are sometimes ordered by courts when proof of paternity is required. In the UK, the Department for Constitutional Affairs accredits bodies which can conduct this testing. The Department of Health is also in the process of updating its voluntary code of practice on genetic paternity testing. The Department for Constitutional Affairs (DCA) is a United Kingdom government department. ... Many governments, both national and more local, have a Department of Health. This article is about the British one. ...


Disproving paternity by use of blood types

A comparison of the blood type of both alleged parents and the child can disprove paternity in some cases. Only certain blood type combinations are possible and a mismatch may prove that the alleged biological father is, in fact, not the father of the child. See the Parent/Child Blood Type Comparison Chart on the website of the Canadian Children's Rights Council.


See also

UK Home Secretary David Blunkett was reported in November 2004 to have started a paternity suit against a former lover. ... Thomas Jefferson There was a long controversy regarding whether or not Thomas Jefferson could have fathered any sons by Sally Hemmings. ... Main articles: Paternity (law) and Paternity testing Paternity fraud, the term, came into common use in the late 1990s describing the act of falsely naming a man to be the biological father of a child when the mother knows (or suspects) that he is not the biological father, particularly for... Genetic fingerprinting or DNA testing is a technique to distinguish between individuals of the same species using only samples of their DNA. Its invention by Sir Alec Jeffreys at the University of Leicester was announced in 1985. ... The Dannielynn Hope Marshall Birkhead paternity case involved the daughter of the then prospective father Larry Birkhead and Vickie Lynn Marshall (better known as Anna Nicole Smith) who was born September 7, 2006 in Nassau, The Bahamas. ...

References

  1. ^ "DNA Paternity Testing in Canada" Canadian Children's Rights Council
  2. ^ "An Earlier Look At Baby's Genes" Science Magazine, U.S.A. VOL 309 2 SEPTEMBER 2005, Published by Advancing Science, Serving Society (AAAS)

External links


  Results from FactBites:
 
Paternity testing - Wikipedia, the free encyclopedia (575 words)
A paternity test is conducted to prove paternity, that is, whether a man is the biological father of another individual.
Meta-analysis of a wide variety of genetic studies appears to show that the rates of non-paternity in the general population are on the order of 4% [1] to over 30%, depending on the social group involved.
Paternity Testing FAQ: a FAQ that covers all the points of a real world DNA testing procedure.
  More results at FactBites »


 

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