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Encyclopedia > Paul Nurse

Sir Paul M. Nurse, FRS, (b. January 25, 1949) is a British biochemist. He was awarded the 2001 Nobel Prize in Physiology or Medicine with Leland H. Hartwell and R. Timothy Hunt for their discoveries regarding cell cycle regulation by cyclin and cyclin dependent kinases. The premises of the Royal Society in London (first four properties only). ... January 25 is the 25th day of the year in the Gregorian calendar. ... Year 1949 (MCMXLIX) was a common year starting on Saturday (the link is to a full 1949 calendar). ... Biochemistry is the chemistry of life. ... 2001 (MMI) was a common year starting on Monday of the Gregorian calendar. ... List of Nobel Prize laureates in Physiology or Medicine from 1901 to the present day. ... Leland H. Hartwell (born October 30, 1939, in Los Angeles, California) is president and director of the Fred Hutchinson Cancer Research Center in Seattle, Washington. ... Dr. R. Timothy (Tim) Hunt (b. ... The cell cycle, or cell-division cycle (CDC), is the series of events in a eukaryotic cell between one cell division and the next. ... Cyclins are a family of proteins involved in the progression of cells through the cell cycle. ... Cyclin-dependent kinase is a protein kinase involved in regulation of the cell cycle. ...


Nurse's parents came from Norfolk. He was born and raised in Wembley, in north-west London, and was educated at Harrow County Grammar School for Boys. He received his undergraduate degree in 1970 from the University of Birmingham and his PhD in 1973 from the University of East Anglia. Beginning in 1976, Nurse identified the gene cdc2 in yeast (Schizosaccharomyces pombe). This gene controls the progression of the cell cycle from G1 phase to S phase and the transition from G2 phase to mitosis. In 1987, Nurse identified the homologous gene in human, CDK1, which codes for a cyclin dependent kinase. Norfolk (pronounced IPA: ) is a low-lying county in East Anglia in the east of southern England. ... Wembley, until 1965 a borough in its own right, forms the northern part of the London Borough of Brent. ... This article is about the capital of England and the United Kingdom. ... Alternative meanings: Harrow, London, a place in the London Borough of Harrow; Harrow School, a famous public school in the United Kingdom; The Harrow, a fantasy and horror magazine. ... Website http://www. ... The University of East Anglia (UEA) is a campus university located in Norwich, Norfolk, England, founded as part of the British Governments New Universities programme in the 1960s. ... Typical divisions Ascomycota Saccharomycotina (true yeasts) Taphrinomycotina Schizosaccharomycetes (fission yeasts) Basidiomycota Basidiomycotina (club fungi) Urediniomycetes Sporidiales Yeasts are unicellular, eukaryotic microorganisms classified in the kingdom Fungi. ... Binomial name Schizosaccharomyces pombe Schizosaccharomyces pombe, also called fission yeast, is a species of yeast. ... The G1 phase is a period in the cell cycle during interphase, between mitosis and the S phase. ... DNA replication. ... G2 phase is a the 3rd and final subphase in interphase of the cell cycle. ... Mitosis divides genetic information during cell division. ... Cyclin-dependent kinase is a protein kinase involved in regulation of the cell cycle. ...


In 1984, Nurse joined the Imperial Cancer Research Fund (ICRF, now named the Cancer Research UK London Research Institute). He left in 1988 to chair the department of microbiology at the University of Oxford. He then returned to the ICRF as Director of Research in 1993, and in 1996 was named Director General of the ICRF, which became the Cancer Research UK London Research Institute in 2002. In 2003, he became president of Rockefeller University in New York City where he continues to work on the cell cycle of fission yeast. The Imperial Cancer Research Fund was a cancer research organization in the United Kingdom. ... This article or section does not cite its references or sources. ... The University of Oxford, located in the city of Oxford, England, is the oldest university in the English-speaking world. ... This article or section does not cite its references or sources. ... Founders Hall Rockefeller University is a private university focusing primarily on graduate and postgraduate education research in the biomedical fields, located between 63rd and 68th Streets along York Avenue, on the Upper East Side of Manhattan island in New York City, New York. ... Nickname: Big Apple, Gotham, NYC Location in the state of New York Coordinates: Country United States State New York Boroughs The Bronx Brooklyn Manhattan Queens Staten Island Settled 1613  - Mayor Michael Bloomberg (R) Area    - City 1,214. ...


In addition to the Nobel Prize, Nurse has received numerous awards and honours. In 1989, he became a fellow of the Royal Society and in 1995 he received a Royal Medal and became a foreign associate of the U.S. National Academy of Sciences. He received the Albert Lasker Award for Basic Medical Research in 1998. Nurse was knighted in 1999. He was awarded the French Legion d'Honneur in 2002. He was also awarded the Copley Medal in 2005. He was elected a Foreign Honorary Member of the American Academy of Arts and Sciences one of the top honours in April 2006. The premises of the Royal Society in London (first four properties only). ... The Royal Medals of the Royal Society of London were established by King George IV. They were further supported with certain changes to their conditions, by King William IV and Queen Victoria. ... President Harding and the National Academy of Sciences at the White House, Washington, DC, April 1921 The National Academy of Sciences (NAS) is a corporation in the United States whose members serve pro bono as advisers to the nation on science, engineering, and medicine. ... The Albert Lasker Award for Basic Medical Research is awarded by the Lasker Foundation for the understanding, diagnosis, prevention, treatment, and cure of disease. ... The silver Anglia knight, commissioned as a trophy in 1850, intended to represent the Black Prince. ... French Legion of Honor The Légion dhonneur (Legion of Honor ( AmE) or Legion of Honour ( ComE)) is an Order of Chivalry awarded by the President of France. ... The Copley Medal is a scientific award for work in any field of science, the highest award granted by the Royal Society of London. ... 2005 (MMV) was a common year starting on Saturday of the Gregorian calendar. ... The House of the Academy, Cambridge, Massachusetts. ...


References

  • Nurse, Paul (2004). The Great Ideas Of Biology: The Romanes Lecture For 2003. Oxford University Press. ISBN 0-19-951897-1. 
  • Les Prix Nobel. 2002. The Nobel Prizes 2001, Editor Tore Frängsmyr. Nobel Foundation: Stockholm.

The Romanes Lecture is a prestigious free public lecture given annually at the Sheldonian Theatre, Oxford. ...

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