A mutiny broke out amongst the troops, disheartened by failure and exasperated by his severity, and Perdiccas was assassinated by some of his officers (321).
As the commander of a battalion of heavy phalanx infantry, Perdiccas distinguished himself at the conquest of Thebes (335 BC), where he was severely wounded.
In the Partition of Babylon made after Alexander's death (323 BC) Alexander's generals agreed that Philip III of Macedon, an epileptic illegitimate son of Alexander's father Philip II of Macedon, and the unborn child of Alexander's wife Roxana should be recognized as joint kings.