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Encyclopedia > Pernicious anaemia

Pernicious anemia refers to a type of autoimmune anemia. Antibodies are directed against intrinsic factor or parietal cells. Intrinsic factor is required for vitamin B12 absorption. The antibodies cause impaired absorption of vitamin B12.


Blood testing typically shows a macrocytic anemia. The serum vitamin B12 level is low. The diagnosis is confirmed by a Schilling test.


Pernicious anemia is treated with vitamin B12 injections (hydroxocobalamin or cyanocobalamin).


The term 'pernicious anemia' is sometimes used more loosely to include non-autoimmune causes of vitamin B12 deficiency.


  Results from FactBites:
 
Tresorie - ANAEMIA AND PERNICIOUS ANAEMIA [Anaemia] (1281 words)
[Both anaemia and pernicious anaemia are currently treated with large daily quantities of liver and liver extracts.
Personal experiments and observations in cases of pernicious anaemia have shown that liver diet by no means represents the remedy for pernicious anaemia.
Unprejudiced observations will show that the nature of pernicious anaemia does not render at all possible an influence of liver diet on the disease picture and on the course of the disease".
PERNICIOUS ANAEMIA (3111 words)
Pernicious anaemia is a condition in which the body does not make enough red blood cells due to a lack of vitamin B12 in the body.
Pernicious anaemia is caused by a lack of vitamin B12 in the body.
Pernicious anaemia is diagnosed using family history and medical history, a physical exam, and diagnostic tests and procedures.
  More results at FactBites »


 

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