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Encyclopedia > Phosphatidyl serine
Phosphatidylserine
Identifiers
CAS number [8002-43-5]
PubChem 445141
Properties
Molecular formula C13H24NO10P
Molar mass 385.304
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Phosphatidylserine is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and rice, and is essential for the normal functioning of neuronal cell membranes. In apoptosis, phosphatidylserine is transferred to the outer leaflet of the plasma membrane. This is part of the process by which the cell is targeted for phagocytosis. Phosphatidylserine (PS) has been used to slow cognitive decline in early-onset Alzheimer's disease. [citation needed] The substance is sold as a dietary supplement to people who believe they can benefit from an increased intake. Image File history File links Structural formula of phosphatidyl serine (Blue/Green: Fatty acid, Black: Glycerol backbone, Red: phosphate, Purple: serine) File history Legend: (cur) = this is the current file, (del) = delete this old version, (rev) = revert to this old version. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... PubChem is a database of chemical molecules. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... Molar mass is the mass of one mole of a chemical element or chemical compound. ... In chemistry, the standard state of a material is its state at 1 bar (100 kilopascals) and 25 degrees Celsius (298. ... Phospholipid Two schematic representations of a phospholipid. ... This article does not cite its references or sources. ... Fish as a food describes the edible parts of water-dwelling, cold-blooded vertebrates with gills, as well as certain other water-dwelling animals such as mollusks, crustaceans, and shellfish. ... Fresh Swiss chard Fresh water spinach Creamed spinach Steamed kale Leaf vegetables, also called potherbs, greens, or leafy greens, are plant leaves eaten as a vegetable, sometimes accompanied by tender petioles and shoots. ... Binomial name Glycine max (L.) Merr. ... Species Oryza glaberrima Oryza sativa Rice is two species of grass (Oryza sativa and Oryza glaberrima) native to tropical and subtropical southern & southeastern Asia and in Africa. ... Drawing by Santiago Ramón y Cajal of neurons in the pigeon cerebellum. ... Illustration of a cell membrane The cell membrane, also called the plasma membrane or plasmalemma, is a semipermeable lipid layer surrounding the cytoplasm of all living cells. ... A cell undergoing apoptosis. ... Phagocytosis (literally cell-eating) is a form of endocytosis wherein large particles are enveloped by the cell membrane of a (usually larger) cell and internalized to form a phagosome, or food vacuole. ...


The dietary supplement was originally processed from cow brains. Prion disease scares in the 1990s outlawed this process, and soon a soy-based alternative was developed. [citation needed]PS sold now is made from plants instead of animals. Transmissible spongiform encephalopathies (TSEs, also known as prion diseases) are a group of progressive conditions that affect the brain and nervous system of humans and animals and are transmitted by prions. ... Binomial name Glycine max Soybeans (US) or soya beans (UK) (Glycine max) are a high-protein legume (Family Fabaceae) grown as food for both humans and livestock. ...


External links

  • DrugBank info page
  • Phosphatidylserine and Cognitive Dysfunction and Dementia
  • MeSH Phosphatidylserines
v • d • e
Lipids: phospholipids

Phosphatidate Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... Lipids are a class of hydrocarbon-containing organic compounds. ... Phospholipid Two schematic representations of a phospholipid. ... Phosphatidate (red: phosphate group, blue & green: fatty acid) Phosphatidates are biochemical compounds that consist of a glycerol backbone, with a (usually) saturated fatty acid bonded to carbon-1, a (usually) unsaturated fatty acid bonded to carbon-2 and a phosphate group bonded to carbon-3. ...


Glycerophospholipids/Phosphoglycerides: Phosphatidylethanolamine - Phosphatidylcholine - Dipalmitoylphosphatidylcholine - Cardiolipin - Phosphatidylserine - ethers (Plasmalogen, Platelet-activating factor)
Phosphatidylinositol - Glycophosphatidylinositol - Phosphatidylinositol 3-phosphate - Phosphatidylinositol (3,4)-bisphosphate - Phosphatidylinositol (3,5)-bisphosphate - Phosphatidylinositol (4,5)-bisphosphate - Phosphatidylinositol (3,4,5)-trisphosphate Glycerophospholipids or phosphoglycerides are glycerol-based phospholipids. ... Phosphatidylethanolamine is a lipid found in biological membranes. ... Lecithin, also known as Phosphatidylcholine Lecithin is usually used as synonym for phosphatidylcholine, a phospholipid which is the major component of a phosphatide fraction which may be isolated from either egg yolk (in Greek lekithos - λεκιθος), or soy beans. ... Dipalmitoylphosphatidylcholine (DPPC) is a phospholipid and the major constituent of pulmonary surfactant. ... Cardiolipin Cardiolipin (alternate image) Cardiolipin (bisphosphatidyl glycerol) is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid. ... A plasmalogen is an ether lipid, with an ether-linked alkene (double bond next to the link), also known as vinyl-ether, at the sn-1 position of the glycerol. ... A platelet-activating factor, also known as a PAF or paf-acether is a potent phospholipid activator and mediator of many leucocyte functions, including platelet aggregation, inflammation, and anaphylaxis. ... Chemical structure of sn-1-stearoyl-2-arachidonoyl phosphatidylinositol Phosphatidylinositol (abbreviated PtdIns, or PI) is a minor phospholipid component of eukaryotic cell membranes. ... A GPI anchor or glycosylphosphatidylinositol is a common posttranslational modification of the C-terminus of membrane-attached proteins. ... Chemical structure of sn-1-stearoyl-2-arachidonoyl phosphatidylinositol 3-phosphate Phosphatidylinositol 3-phosphate (PtdIns3P) is the product of both the class II and III phosphoinositide 3-kinases (PI 3-kinases) activity on Phosphatidylinositol. ... Chemical structure of sn-1-stearoyl-2-arachidonoyl phosphatidylinositol (3,4)-bisphosphate Phosphatidylinositol (3,4)-bisphosphate (PtdIns(3,4)P2) is a minor phospholipid component of cell membranes, it is however an important second messenger. ... Chemical structure of sn-1-stearoyl-2-arachidonoyl phosphatidylinositol (3,5)-bisphosphate Phosphatidylinositol (3,5)-bisphosphate (PtdIns(3,5)P2) is a minor phospholipid component of cell membranes, it however is important in distinguishing cell compartments. ... Chemical structure of sn-1-stearoyl-2-arachidonoyl phosphatidylinositol 4,5-bisphosphate Phosphatidylinositol (4,5)-bisphosphate (PtdIns(4,5)P2) is a minor phospholipid component of cell membranes. ... Chemical structure of sn-1-stearoyl-2-arachidonoyl phosphatidylinositol 3,4,5-trisphosphate Phosphatidylinositol (3,4,5)-trisphosphate (PtdIns(3,4,5)P3) commonly abbreviated to PIP3 is the product of the class I phosphoinositide 3-kinases (PI 3-kinases) activity on Phosphatidylinositol (4,5)-bisphosphate. ...


Sphingomyelin Sphingomyelin is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath which surrounds some nerve cell axons. ...


  Results from FactBites:
 
Phosphatidylserine (Phosphatidyl Serine) Normalizes Brain Function; Boosts the Weak Stress Response (3442 words)
Phosphatidyl serine (phosphatidylserine): Flavay Plus® is formulated with phosphatidyl serine (Leci-PS™), a complex of amino and fatty acids extracted from soy lecithin, which has proven to be a safe, potentially effective therapeutic agent in treating memory deficit disorders and is an often-used supplement for attention deficit disorders.
Phosphatidyl serine is a phospholipid that is vital to brain cell structure and function.
Phosphatidyl serine may have the capacity to normalize the stress-induced activation of the "fight or flight response." In a double-blind, placebo-controlled study conducted in Italy, phosphatidyl serine lowered stress hormone (cortisol) production by 30 percent.
  More results at FactBites »


 

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