Phosphoribosyl pyrophosphate
Identifiers
CAS number	7540-64-9
PubChem	7339
MeSH	Phosphoribosyl+pyrophosphate
Properties
Molecular formula	C5H13O14P3
Molar mass	390.07 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Phosphoribosyl pyrophosphate (PRPP) is a pentosephosphate. CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... PubChem is a database of chemical molecules. ... Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... A chemical formula is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... Molar mass is the mass of one mole of a chemical element or chemical compound. ... The plimsoll symbol as used in shipping In chemistry, the standard state of a material is its state at 1 bar (100 kilopascals exactly). ... Glucose-6-phosphate Phytic acid Sugar phosphates (sugars that have added or substituted phosphate groups) are often used in biological systems to store or transfer energy. ...

It is formed from ribose 5-phosphate by the enzyme ribose-phosphate diphosphokinase. Ribose-phosphate diphosphokinase (or phosphoribosyl pyrophosphate synthetase) is an enzyme which converts ribose 5-phosphate into phosphoribosyl pyrophosphate. ...

It plays a role in transferring phosphate groups in several reactions:

In de novo generation of purines, the enzyme amidophosphoribosyltransferase acts upon PRPP to create phosphoribosylamine. Adenine phosphoribosyltransferase (or APRTase) is an enzyme involved in the purine salvage pathway. ... For the programming language Adenine, see Adenine (programming language). ... Adenosine monophosphate, also known as 5-adenylic acid and abbreviated AMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside adenosine. ... Hypoxanthine-guanine phosphoribosyltransferase (HPRT) is an enzyme (EC 2. ... Guanine is one of the five main nucleobases found in the nucleic acids DNA and RNA; the others being adenine, cytosine, thymine, and uracil. ... Guanosine monophosphate, also known as 5-guanidylic acid and abbreviated GMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside guanosine. ... Hypoxanthine is a naturally occurring purine derivative, and one of the products of the action of xanthine oxidase on xanthine, though more normally in purine degradation, hypoxanthine is oxidized by xanthine oxidase to form xanthine. ... Inosine monophosphate (IMP) is an inosine nucleotide. ... Uracil phosphoribosyltransferase is an enzyme which creates UMP from uracil and phosphoribosylpyrophosphate. ... Uracil is a pyrimidine which is common and naturally occurring. ... Uridine monophosphate, also known as 5-uridylic acid and abbreviated UMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside uridine. ... In general usage, de novo is a Latin expression meaning afresh, anew, beginning again. In USA Banking, a de novo bank is defined as a state member bank that has been in operation for five years or less. ... Amidophosphoribosyltransferase (or phosphoribosyl pyrophosphate amidotransferase) is an enzyme which converts phosphoribosylpyrophosphate (PRPP) into 5-phosphoribosylamine. ...

See also

• Pyrimidine biosynthesis