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Encyclopedia > Pneumocystis carinii
Pneumocystis jiroveci
Scientific classification
Domain: Eukaryota
Kingdom: Fungi
Phylum: Ascomycota
Class: Pneumocystidomycetes
Order: Pneumocystidales
Family: Pneumocystidaceae
Genus: Pneumocystis
Species: P. jiroveci
Binomial name
Pneumocystis jiroveci

Pneumocystis jiroveci, also known by its former name Pneumocystis carinii, is a fungus (earlier classified as a protozoa) that causes pneumocystis carinii pneumonia (PCP). It affects those with weakened immune systems such as children and the elderly, but is especially common in patients with AIDS. It is diagnosed by silver staining of the sputum.


In immunocompromised patients (e.g. those on chemotherapy or AIDS with a low CD4+ count; below 200/mm³), prophylaxis with regular pentamidine inhalations or sulfamethoxazole/trimethoprim (co-trimoxazole or TMP-SMX) may be necessary.


It is distributed world wide.


  Results from FactBites:
 
Pneumocystis Pneumonia (544 words)
Pneumocystis carinii pneumonia (PCP) is an infection caused by Pneumocystis carinii, a microscopic fungus that lives in the lungs of many people.
Pneumocystis pneumonia is the most common pediatric illness associated with AIDS, especially in infants younger than 6 months, and its prevention is very important in AIDS care.
Some of the different antibiotics that may be used to treat pneumocystis may have side effects, which are easier to monitor in a hospital.
p031113b - Pneumocystis Carinii - Colonization (1099 words)
However, a low level of P. carinii organisms undetectable by microscopy was detected in BAL fluid by two subsequent nested PCR assays: one assay amplifying a portion of the mitochondrial large subunit RNA gene and a second one amplifying the internal transcribed spacers (ITS) 1 and ITS 2 of the nuclear rRNA operon.
In HIV-infected patients, P. carinii DNA was detected by nested PCR in blood samples from 3 of 14 patients with microscopically proven P. carinii pneumonia, 7 of 22 patients who were considered to be colonized with P. carinii, and 9 of 48 patients who were neither infected nor colonized with P. carinii.
Abstract: A prospective study was undertaken to evaluate the incidence and the course of Pneumocystis carinii colonization in immunocompetent patients with severe pulmonary diseases.
  More results at FactBites »


 

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