|
Polyarteritis nodosa (or periarteritis nodosa) is a serious blood vessel disease. Small and medium-sized arteries become swollen and damaged when they are attacked by rogue immune cells. Polyarteritis nodosa is also called Kussmaul disease or Kussmaul-Meier disease. The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ...
The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ...
// M00-M99 - Diseases of the musculoskeletal system and connective tissue (M00-M25) Arthropathies (M00-M03) Infectious arthropathies (M00) Pyogenic arthritis (M01) Direct infections of joint in infectious and parasitic diseases classified elsewhere (M02) Reactive arthropathies (M023) Reiters disease (M03) Postinfective and reactive arthropathies in diseases classified elsewhere (M05-M14...
The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ...
The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ...
The Disease Bold textDatabase is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ...
MedlinePlus (medlineplus. ...
eMedicine is an online clinical medical knowledge base that was founded in 1996. ...
Adolph Kussmaul (1822 - 1902) was a German physician. ...
Causes and risk factors Polyarteritis nodosa is a disease of unknown cause that affects arteries, the blood vessels that carry oxygenated blood to organs and tissues. It occurs when certain immune cells attack the affected arteries.
Incidence The condition affects adults more frequently than children. It damages the tissues supplied by the affected arteries because they don't receive enough oxygen and nourishment without a proper blood supply. Polyarteritis nodosa is more common in people with hepatitis B infection. Hepatitis is inflammation of the liver. ...
Symptoms In this disease, symptoms result from damage to affected organs, often the skin, heart, kidneys, and nervous system.
Generalised symptoms include fever, fatigue, weakness, loss of appetite, and weight loss. Muscle and joint aches are common. The skin may show rashes, swelling, ulcers, and lumps.
Nerve involvement may causeujgjg sensory changes with numbness, pain, burning, and weaknessCentral nervous system involvement may cause strokes or seizures. Kidney involvement can produce varying degrees of renal failure.
Involvement of the arteries of the heart may cause a heart attack, heart failure, and inflammation of the sac around the heart (pericarditis).
The word fatigue is used in everyday living to describe a range of afflictions, varying from a general state of lethargy to a specific work induced burning sensation within muscle. ...
Weakness can mean: The opposite of strength Weakness (medical) This is a disambiguation page — a navigational aid which lists pages that might otherwise share the same title. ...
An analogue medical thermometer showing the temperature of 38. ...
Abdominal pain can be one of the symptoms associated with transient disorders or serious disease. ...
Anorexia (deriving from the Greek ÏŒÏεξη (orexe) = appetite) is the decreased sensation of appetite. ...
Weight loss, in the context of medicine or health, is a reduction of the total body weight, which can mean loss of fluid, muscle, bone mass, or fat. ...
Myalgia means muscle pain and is a symptom of many diseases and disorders. ...
In medicine, arthralgia (literally: joint pain, from arthros = joint and -algia denoting pain) is the presence of painful joints in the absence of frank arthritis. ...
Signs and tests There are no specific lab tests for diagnosing polyarteritis nodosa. Diagnosis is generally based upon the physical examination and a few laboratory studies that help to confirm the diagnosis: - Perinuclear pattern of antineutrophil cytoplasmic antibodies (p-ANCA) (high titers are often present in the serum and correlates with disease activity, primarily in small vessel disease). P-ANCA is never associated with classic polyarteritis nodosa, and is more present in microscopic forms of the disease known as microscopic polyangiitis or leukocytoclastic angiitis.
- CBC (may demonstrate an elevated white blood count)
- ESR (often elevated)
- Tissue biopsy (reveals inflammation in small arteries, called arteritis)
Anti-neutrophil cytoplasmic antibodies (ANCAs) are antibodies against antigens in the cytoplasm of neutrophil granulocytes (the most common type of white blood cell). ...
Microscopic polyangiitis is an ill-defined autoimmune disease which usually presents with pulmonary bleeding and anemia. ...
Schematics of shorthand for complete blood count commonly used by physicians. ...
The erythrocyte sedimentation rate(ESR), also called a sedimentation rate, sed rate or Biernacki Reaction, is a non-specific measure of inflammation that is commonly used as a medical screening test. ...
Arteritis is inflammation of the walls of arteries, usually as a result of infection or auto-immune response. ...
Treatment Treatment involves medications to suppress the immune system, including prednisone and cyclophosphamide. This article or section does not adequately cite its references or sources. ...
Cyclophosphamide (the generic name for Cytoxan, Neosar) is a nitrogen mustard alkylating agent, used to treat various types of cancer and some autoimmune disorders. ...
Expectations (prognosis) Current treatments using steroids and other drugs that suppress the immune system (such as cyclophosphamide) can improve symptoms and the chance of long-term survival. The most serious associated conditions generally involve the kidneys and gastrointestinal tract. Without treatment, the outlook is poor.
Complications A stroke, also known as cerebrovascular accident (CVA),[1] is an acute neurological injury in which the blood supply to a part of the brain is interrupted. ...
Renal failure is when the kidneys fail to function properly. ...
Acute myocardial infarction (AMI or MI), commonly known as a heart attack, is a disease state that occurs when the blood supply to a part of the heart is interrupted. ...
Necrosis (in Greek ÎεκÏός = Death) is the name given to accidental death of cells and living tissue. ...
Prevention This disease cannot currently prevented, but early treatment can prevent some damage and symptoms.
External links | 
Feeds |
Contact