In Greek mythology, there were several individuals named Polydora:

1. Polydora was the daughter of either Peleus and Antigone, or Perieres and Gorgophone. An affair with Sperchius led to the birth of Menesthius; she also had an affair with Peleus. Her husband was Borus.
2. Polydora was the daughter of Meleager and Cleopatra (not the Egyptian Cleopatra), and the wife of Protesilaus. After her husband's death, she crafted an image of him and enjoyed its company. Hermes took pity and returned her husband from Hades, but when the shade tried to return to the underworld with his wife, she committed suicide.
3. Polydora was one of the Oceanids.
4. Polydora was the daughter of Danaus (but was not one of the Danaids). With Sperchius she was mother to Dryops.
5. Polydora was one of the amazons.